Bus from Rome to Frankfurt am Main from $61

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Rome to Frankfurt am Main

Here is a selection of the cheapest bus trips from the schedule from Rome to Frankfurt am Main from various bus operators like FlixBus for the next days.

today
$81
tomorrow
$82
Sunday
$82
Monday
$71
Tuesday
$71
Wednesday
$73
Thursday
$66

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 11:35 PM Rome Anagnina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $81
FlixBus 22h 55m 11:50 PM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $82
FlixBus 19h 50m 10:05 PM Rome Tiburtina Bus Station 5:55 PM Frankfurt am Main Central Station  Economy $85
FlixBus 22h 30m 12:15 AM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $93
FlixBus 20h 55m 4:35 PM Rome Tiburtina Bus Station 1:30 PM Frankfurt am Main Central Station  Economy $93
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $55
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 1h 5m longer, but you will save $13

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 30m 12:15 AM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $82
FlixBus 19h 20m 10:40 AM Rome Tiburtina Bus Station 6:00 AM Frankfurt am Main Central Station  Economy $82
FlixBus 20h 55m 4:35 PM Rome Tiburtina Bus Station 1:30 PM Frankfurt am Main Central Station  Economy $85
FlixBus 19h 40m 5:25 PM Rome Anagnina Bus Station 1:05 PM Frankfurt am Main Central Station  Economy $87
FlixBus 20h 15m 9:35 AM Rome Tiburtina Bus Station 5:50 AM Frankfurt am Main Central Station  Economy $88
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $55
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 1h 35m longer, but you will save $14

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 11:35 PM Rome Anagnina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $82
FlixBus 19h 20m 10:40 AM Rome Tiburtina Bus Station 6:00 AM Frankfurt am Main Central Station  Economy $85
FlixBus 22h 55m 11:50 PM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $85
FlixBus 20h 10m 9:45 PM Rome Tiburtina Bus Station 5:55 PM Frankfurt am Main Central Station  Economy $86
FlixBus 20h 55m 4:35 PM Rome Tiburtina Bus Station 1:30 PM Frankfurt am Main Central Station  Economy $91
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $22? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $51
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $9
    Travel time is 1h 35m longer, but you will save $22

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 55m 4:35 PM Rome Tiburtina Bus Station 1:30 PM Frankfurt am Main Central Station  Economy $71
FlixBus 25h 10m 9:20 PM Rome Tiburtina Bus Station 10:30 PM Frankfurt am Main Central Station  Economy $75
FlixBus 22h 55m 11:50 PM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $75
FlixBus 22h 55m 11:50 AM Rome Tiburtina Bus Station 10:45 AM Frankfurt am Main Central Station  Economy $77
FlixBus 22h 15m 8:00 PM Rome Tiburtina Bus Station 6:15 PM Frankfurt am Main Central Station  Economy $77
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $48
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $9
    Travel time is the same as the direct connection, but you will save $13

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 55m 4:35 PM Rome Tiburtina Bus Station 1:30 PM Frankfurt am Main Central Station  Economy $71
FlixBus 22h 55m 11:50 PM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $77
FlixBus 21h 40m 1:05 PM Rome Anagnina Bus Station 10:45 AM Frankfurt am Main Central Station  Economy $79
FlixBus 21h 20m 8:30 AM Rome Tiburtina Bus Station 5:50 AM Frankfurt am Main Central Station  Economy $80
FlixBus 22h 15m 8:00 PM Rome Tiburtina Bus Station 6:15 PM Frankfurt am Main Central Station  Economy $80
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $48
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $9
    Travel time is the same as the direct connection, but you will save $13

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 55m 4:35 PM Rome Tiburtina Bus Station 1:30 PM Frankfurt am Main Central Station  Economy $73
FlixBus 23h 10m 11:35 PM Rome Anagnina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $75
FlixBus 21h 35m 10:55 PM Rome Tiburtina Bus Station 8:30 PM Frankfurt am Main Central Station  Economy $77
FlixBus 22h 55m 11:50 PM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $77
FlixBus 21h 55m 8:00 PM Rome Tiburtina Bus Station 5:55 PM Frankfurt am Main Central Station  Economy $78
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $15? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $48
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $9
    Travel time is the same as the direct connection, but you will save $15

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 8:00 PM Rome Tiburtina Bus Station 6:15 PM Frankfurt am Main Central Station  Economy $66
FlixBus 21h 35m 10:55 PM Rome Tiburtina Bus Station 8:30 PM Frankfurt am Main Central Station  Economy $66
FlixBus 21h 40m 1:05 PM Rome Anagnina Bus Station 10:45 AM Frankfurt am Main Central Station  Economy $67
FlixBus 19h 50m 10:10 AM Rome Tiburtina Bus Station 6:00 AM Frankfurt am Main Central Station  Economy $68
FlixBus 22h 30m 12:15 AM Rome Tiburtina Bus Station 10:45 PM Frankfurt am Main Central Station  Economy $72
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $8? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $48
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $9
    Travel time is 1h 5m longer, but you will save $8

Best Price Offer: The price for the cheapest bus from Rome to Frankfurt am Main is $61 on 2/23/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Rome and Frankfurt am Main

See here how frequent the connections between Rome and Frankfurt am Main are, during different times and days of the week.
Thursday is the busiest day, with more than 12 daily buses from Rome to Frankfurt am Main. Tuesday has instead the fewest connections, with only 6 daily coaches between Rome and Frankfurt am Main.
The busiest time of the day is the Evening, with 25 buses from Rome to Frankfurt am Main, while Night sees the fewest connections between Rome and Frankfurt am Main, with 5 offers.

Facts about the bus from Rome to Frankfurt am Main

Compare all providers like FlixBus that travel 10 times every day by bus from Rome to Frankfurt am Main in one click! Book your bus ticket from Rome to Frankfurt am Main starting from $61!

Cheapest Bus $61
Fastest Bus 19h 20m
Earliest Bus 12:15 AM
Latest Bus 11:50 PM
Daily Bus Routes 10 Ø
Distance 596.0 miles
Bus Companies FlixBus

Cheapest bus connections from Rome to Frankfurt am Main

Every day, 10 buses from 1 bus companies leave Rome for Frankfurt am Main: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
$81
Saturday 02/07
$83
Sunday 02/08
$83
Monday 02/09
$71
Tuesday 02/10
$71
Wednesday 02/11
$73
Thursday 02/12
$66
Friday 02/13
$70
Saturday 02/14
$68
Sunday 02/15
$74
Monday 02/16
$67
Tuesday 02/17
$68
Wednesday 02/18
$67
Thursday 02/19
$67
Friday 02/20
$65
Saturday 02/21
$70
Sunday 02/22
$80
Monday 02/23
$61
Tuesday 02/24
$61
Wednesday 02/25
$61
Thursday 02/26
$63
Friday 02/27
$65
Saturday 02/28

The cheapest time to travel from Rome to Frankfurt am Main

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Frankfurt am Main, for the next 30 days.
With a price starting from $61, Monday is the cheapest day for a bus from Rome to Frankfurt am Main. Sunday instead is the most expensive day with prices starting from $73.
Night is the cheapest day time for bus tickets from Rome to Frankfurt am Main, with $61. Morning is the most expensive time of the day with prices starting from $68.

How to save money travelling from Rome to Frankfurt am Main

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Frankfurt am Main in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Frankfurt am Main, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Frankfurt am Main are also emptier.

All bus stations and stops in Rome and Frankfurt am Main

In the map below, you can see where to find all bus stations in Rome and Frankfurt am Main.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Frankfurt am Main? Compare all modes of transports from Rome to Frankfurt am Main.

Service and Comfort on the bus from Rome to Frankfurt am Main

Want to know which seat classes are available on the buses from Rome to Frankfurt am Main? Or which bus companies serve the route Rome to Frankfurt am Main? Below you will find answers to your questions.

FAQs about the Rome to Frankfurt am Main bus

How much does a Rome Frankfurt am Main bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $61 and takes 22h 15m to reach Frankfurt am Main. Compare offers to save money!

How much could I save by comparing buses from Rome to Frankfurt am Main?

This route is offered by 1 companies with a range of ticket prices between $61 and $128. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frankfurt am Main.

On average, how many connections are available from Rome to Frankfurt am Main each day?

Every day, the Rome to Frankfurt am Main bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Frankfurt am Main take?

The fastest bus from Rome to Frankfurt am Main is offered by FlixBus and takes 19h 20m. Bus tickets for this connection cost $82. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Frankfurt am Main?

The earliest bus arriving in Frankfurt am Main from Rome starts at 12:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Frankfurt am Main?

The latest bus trip departing from Rome for Frankfurt am Main starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Frankfurt am Main route?

When traveling by bus from Rome to Frankfurt am Main, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Frankfurt am Main?

You can check all the direct connections between Rome and Frankfurt am Main by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Frankfurt am Main bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Frankfurt am Main bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Frankfurt am Main bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Frankfurt am Main on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Frankfurt am Main?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Rome and Frankfurt am Main. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Frankfurt am Main?

Prices and availability for 10 trips between Rome and Frankfurt am Main change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Frankfurt am Main

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Frankfurt am Main

Here’s an overview of the most popular bus routes to Rome and to Frankfurt am Main. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Milazzo to Rome Bus from Milazzo to Rome
Bus Agrigento to Rome Bus Agrigento to Rome
Buses Altamura - Rome Buses Altamura - Rome
Buses Giulianova to Rome Buses Giulianova to Rome
Bus from Tarbes to Frankfurt am Main Bus from Tarbes to Frankfurt am Main
Buses Barcelona to Frankfurt am Main Buses Barcelona to Frankfurt am Main
Bus Ostrava - Frankfurt am Main Bus Ostrava - Frankfurt am Main
Buses from Linz to Frankfurt am Main Buses from Linz to Frankfurt am Main
Popular Airport Shuttles to Rome and to Frankfurt am Main
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Frankfurt am Main

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.