Bus Rome to Frankfurt am Main: Compare prices and save money

Compare all timetables for the bus from Rome to Frankfurt am Main

Here is a selection of the cheapest bus trips from the schedule from Rome to Frankfurt am Main from various bus operators like FlixBus for the next days.

today

$123

tomorrow

$153

Sunday

$150

Monday

$132

Tuesday

$132

Wednesday

$118

Thursday

$122

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 10m	11:35 PM	Rome	Anagnina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$123	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 11:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/20/2025 10:45:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 10m
FlixBus	22h 55m	11:50 PM	Rome	Tiburtina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$124	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 11:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/20/2025 10:45:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 22h 55m
FlixBus	21h 35m	10:55 PM	Rome	Tiburtina Bus Station	8:30 PM	Frankfurt am Main	Central Station	Economy	$125	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 10:55:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/20/2025 8:30:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 21h 35m
FlixBus	21h 40m	1:05 PM	Rome	Anagnina Bus Station	10:45 AM	Frankfurt am Main	Central Station	Economy	$141	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 1:05:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/20/2025 10:45:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 21h 40m
FlixBus	27h 5m	5:25 PM	Rome	Anagnina Bus Station	8:30 PM	Frankfurt am Main	Central Station	Economy	$142	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 5:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/20/2025 8:30:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 27h 5m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $19? You can find the corresponding connections below.
- Distribusion
  
  28h 30m
  
  0
  
  9:45 PM
  
  Rome
  Tiburtina Bus Station
  
  9:50 AM
  
  Verona
  Viale Palladio Bus Stop
  
  0
  
  Premium Economy
  
  $28
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 9:45:00 PM to Viale Palladio Bus Stop, Verona (Italy) arriving at 12/21/2025 9:50:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 12h 5m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $76
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/21/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 25m
Travel time is 6h 55m longer, but you will save $19

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 30m	12:15 AM	Rome	Tiburtina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$153	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 12:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/20/2025 10:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 22h 30m
FlixBus	19h 20m	10:40 AM	Rome	Tiburtina Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$153	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 10:40:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/21/2025 6:00:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 19h 20m
FlixBus	22h 55m	11:50 PM	Rome	Tiburtina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$153	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 11:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/21/2025 10:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 22h 55m
FlixBus	23h 10m	11:35 PM	Rome	Anagnina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$153	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 11:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/21/2025 10:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 23h 10m
FlixBus	20h 55m	4:35 PM	Rome	Tiburtina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$155	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 4:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/21/2025 1:30:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 20h 55m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $49? You can find the corresponding connections below.
- Distribusion
  
  28h 30m
  
  0
  
  9:45 PM
  
  Rome
  Tiburtina Bus Station
  
  9:50 AM
  
  Verona
  Viale Palladio Bus Stop
  
  0
  
  Premium Economy
  
  $28
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 9:45:00 PM to Viale Palladio Bus Stop, Verona (Italy) arriving at 12/21/2025 9:50:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 12h 5m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $76
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/21/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 25m
Travel time is 9h 10m longer, but you will save $49

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 55m	4:35 PM	Rome	Tiburtina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$150	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 4:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 1:30:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 20h 55m
FlixBus	23h 10m	11:35 PM	Rome	Anagnina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$157	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 11:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 10:45:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 23h 10m
FlixBus	19h 20m	10:40 AM	Rome	Tiburtina Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$159	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:40:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 6:00:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 19h 20m
FlixBus	22h 55m	11:50 PM	Rome	Tiburtina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$159	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 11:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 10:45:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 22h 55m
FlixBus	22h 30m	12:15 AM	Rome	Tiburtina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$165	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 12:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/21/2025 10:45:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 22h 30m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $46? You can find the corresponding connections below.
- Distribusion
  
  28h 30m
  
  0
  
  9:45 PM
  
  Rome
  Tiburtina Bus Station
  
  9:50 AM
  
  Verona
  Viale Palladio Bus Stop
  
  0
  
  Premium Economy
  
  $28
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 9:45:00 PM to Viale Palladio Bus Stop, Verona (Italy) arriving at 12/21/2025 9:50:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 12h 5m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $76
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/21/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 25m
Travel time is 9h 10m longer, but you will save $46

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 55m	4:35 PM	Rome	Tiburtina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$132	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 4:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/23/2025 1:30:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 55m
FlixBus	24h 35m	1:40 AM	Rome	Tiburtina Bus Station	2:15 AM	Frankfurt am Main	Central Station	Economy	$136	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 1:40:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/23/2025 2:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 24h 35m
FlixBus	22h 30m	12:15 AM	Rome	Tiburtina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$137	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 12:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 10:45:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 22h 30m
FlixBus	23h 30m	9:00 PM	Rome	Tiburtina Bus Station	8:30 PM	Frankfurt am Main	Central Station	Economy	$137	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 9:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/23/2025 8:30:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 30m
FlixBus	21h 40m	1:05 PM	Rome	Anagnina Bus Station	10:45 AM	Frankfurt am Main	Central Station	Economy	$137	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 1:05:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/23/2025 10:45:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 21h 40m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $28? You can find the corresponding connections below.
- Distribusion
  
  28h 30m
  
  0
  
  9:45 PM
  
  Rome
  Tiburtina Bus Station
  
  9:50 AM
  
  Verona
  Viale Palladio Bus Stop
  
  0
  
  Premium Economy
  
  $28
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 9:45:00 PM to Viale Palladio Bus Stop, Verona (Italy) arriving at 12/21/2025 9:50:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 12h 5m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $76
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/21/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 25m
Travel time is 7h 35m longer, but you will save $28

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 55m	4:35 PM	Rome	Tiburtina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$132	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 4:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/24/2025 1:30:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 55m
FlixBus	23h 30m	9:00 PM	Rome	Tiburtina Bus Station	8:30 PM	Frankfurt am Main	Central Station	Economy	$136	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 9:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/24/2025 8:30:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 30m
FlixBus	21h 40m	1:05 PM	Rome	Anagnina Bus Station	10:45 AM	Frankfurt am Main	Central Station	Economy	$141	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/23/2025 1:05:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/24/2025 10:45:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 21h 40m
FlixBus	21h 45m	9:30 AM	Rome	Tiburtina Bus Station	7:15 AM	Frankfurt am Main	Central Station	Economy	$142	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 9:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/24/2025 7:15:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 21h 45m
FlixBus	24h 35m	1:40 AM	Rome	Tiburtina Bus Station	2:15 AM	Frankfurt am Main	Central Station	Economy	$148	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:40:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/24/2025 2:15:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 24h 35m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $30? You can find the corresponding connections below.
- FlixBus
  
  27h 30m
  
  0
  
  10:45 PM
  
  Rome
  Tiburtina Bus Station
  
  7:00 AM
  
  Verona
  Porta Nuova Bus Station
  
  0
  
  Economy
  
  $33
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 10:45:00 PM to Porta Nuova Bus Station, Verona (Italy) arriving at 12/24/2025 7:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 15m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $69
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/24/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 2:15:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 12h 25m
Travel time is 6h 35m longer, but you will save $30

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 55m	4:35 PM	Rome	Tiburtina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$118	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 4:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 1:30:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 20h 55m
FlixBus	21h 5m	5:25 PM	Rome	Anagnina Bus Station	2:30 PM	Frankfurt am Main	Central Station	Economy	$127	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 5:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 2:30:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 21h 5m
FlixBus	21h 35m	10:55 PM	Rome	Tiburtina Bus Station	8:30 PM	Frankfurt am Main	Central Station	Economy	$129	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 10:55:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 8:30:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 21h 35m
FlixBus	19h 50m	10:10 AM	Rome	Tiburtina Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$131	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 10:10:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 6:00:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 19h 50m
FlixBus	23h 10m	11:35 PM	Rome	Anagnina Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$131	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 11:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 10:45:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 10m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $16? You can find the corresponding connections below.
- FlixBus
  
  27h 30m
  
  0
  
  10:45 PM
  
  Rome
  Tiburtina Bus Station
  
  7:00 AM
  
  Verona
  Porta Nuova Bus Station
  
  0
  
  Economy
  
  $33
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 10:45:00 PM to Porta Nuova Bus Station, Verona (Italy) arriving at 12/24/2025 7:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 15m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $69
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/24/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 2:15:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 12h 25m
Travel time is 7h 40m longer, but you will save $16

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 55m	4:35 PM	Rome	Tiburtina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$122	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 4:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/26/2025 1:30:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 20h 55m
FlixBus	19h 50m	10:10 AM	Rome	Tiburtina Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$128	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 10:10:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/26/2025 6:00:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 19h 50m
FlixBus	21h 20m	8:30 AM	Rome	Tiburtina Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$130	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 8:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/26/2025 5:50:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 20m
FlixBus	26h 20m	11:10 AM	Rome	Anagnina Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$130	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/25/2025 11:10:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 12/26/2025 1:30:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 26h 20m
FlixBus	23h 20m	5:25 PM	Rome	Anagnina Bus Station	4:45 PM	Frankfurt am Main	Central Station	Economy	$131	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/25/2025 5:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/26/2025 4:45:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 20m

Did you know that if you travel from Rome to Frankfurt am Main via Verona, you can save more than $20? You can find the corresponding connections below.
- FlixBus
  
  27h 30m
  
  0
  
  10:45 PM
  
  Rome
  Tiburtina Bus Station
  
  7:00 AM
  
  Verona
  Porta Nuova Bus Station
  
  0
  
  Economy
  
  $33
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 10:45:00 PM to Porta Nuova Bus Station, Verona (Italy) arriving at 12/24/2025 7:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 15m
- FlixBus
  
  12h 25m
  
  0
  
  1:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  2:15 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $69
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 12/24/2025 1:50:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 12/25/2025 2:15:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 12h 25m
Travel time is 7h 40m longer, but you will save $20

Best Price Offer: The price for the cheapest bus from Rome to Frankfurt am Main is $82 on 1/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Rome and Frankfurt am Main

See here how frequent the connections between Rome and Frankfurt am Main are, during different times and days of the week.

Sunday is the busiest day, with more than 12 daily buses from Rome to Frankfurt am Main. Friday has instead the fewest connections, with only 9 daily coaches between Rome and Frankfurt am Main.

The busiest time of the day is the Evening, with 26 buses from Rome to Frankfurt am Main, while Night sees the fewest connections between Rome and Frankfurt am Main, with 9 offers.

Facts about the bus from Rome to Frankfurt am Main

Compare all providers like FlixBus that travel 10 times every day by bus from Rome to Frankfurt am Main in one click! Book your bus ticket from Rome to Frankfurt am Main starting from $82!

Cheapest Bus	$82
Fastest Bus	19h 20m
Earliest Bus	10:40 AM
Latest Bus	11:50 PM
Daily Bus Routes	10 Ø
Distance	596.0 miles
Bus Companies	FlixBus

Cheapest bus connections from Rome to Frankfurt am Main

Every day, 10 buses from 1 bus companies leave Rome for Frankfurt am Main: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$123

Saturday 12/20

$153

Sunday 12/21

$150

Monday 12/22

$132

Tuesday 12/23

$132

Wednesday 12/24

$118

Thursday 12/25

$122

Friday 12/26

$129

Saturday 12/27

$132

Sunday 12/28

$142

Monday 12/29

$142

Tuesday 12/30

$142

Wednesday 12/31

$122

Thursday 01/01

$142

Friday 01/02

$169

Saturday 01/03

$179

Sunday 01/04

$155

Monday 01/05

$110

Tuesday 01/06

$114

Wednesday 01/07

$90

Thursday 01/08

$82

Friday 01/09

$83

Saturday 01/10

The cheapest time to travel from Rome to Frankfurt am Main

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Frankfurt am Main, for the next 30 days.

With a price starting from $59, Wednesday is the cheapest day for a bus from Rome to Frankfurt am Main. Friday instead is the most expensive day with prices starting from $83.

Night is the cheapest day time for bus tickets from Rome to Frankfurt am Main, with $59. Morning is the most expensive time of the day with prices starting from $128.

How to save money travelling from Rome to Frankfurt am Main

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Frankfurt am Main in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Frankfurt am Main, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Frankfurt am Main are also emptier.

All bus stations and stops in Rome and Frankfurt am Main

In the map below, you can see where to find all bus stations in Rome and Frankfurt am Main.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Central Bus Station

Karlsruher Straße 10

Stuttgarter Strasse Bus Stop

Stuttgarter Str.

Seilerstraße Bus Stop

Baseler Platz Bus Stop

Stresemannallee/Mörfelder Landstr. Bus Stop

Service and Comfort on the bus from Rome to Frankfurt am Main

Want to know which seat classes are available on the buses from Rome to Frankfurt am Main? Or which bus companies serve the route Rome to Frankfurt am Main? Below you will find answers to your questions.

FAQs about the Rome to Frankfurt am Main bus

How much does a Rome Frankfurt am Main bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $82 and takes 20h 55m to reach Frankfurt am Main. Compare offers to save money!

How much could I save by comparing buses from Rome to Frankfurt am Main?

This route is offered by 1 companies with a range of ticket prices between $82 and $211. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frankfurt am Main.

On average, how many connections are available from Rome to Frankfurt am Main each day?

Every day, the Rome to Frankfurt am Main bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Frankfurt am Main take?

The fastest bus from Rome to Frankfurt am Main is offered by FlixBus and takes 19h 20m. Bus tickets for this connection cost $153. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Frankfurt am Main?

The earliest bus arriving in Frankfurt am Main from Rome starts at 10:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Frankfurt am Main?

The latest bus trip departing from Rome for Frankfurt am Main starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Frankfurt am Main route?

When traveling by bus from Rome to Frankfurt am Main, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Frankfurt am Main?

You can check all the direct connections between Rome and Frankfurt am Main by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Frankfurt am Main bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Frankfurt am Main bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Frankfurt am Main bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Frankfurt am Main on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Frankfurt am Main?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Rome and Frankfurt am Main. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Frankfurt am Main?

Prices and availability for 10 trips between Rome and Frankfurt am Main change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Frankfurt am Main

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Frankfurt am Main

Here’s an overview of the most popular bus routes to Rome and to Frankfurt am Main. Simply click on the connection of your choice, and you will find all the details about your bus route!