Bus Palermo to Milan: Compare prices and save money

Compare all timetables for the bus from Palermo to Milan

Here is a selection of the cheapest bus trips from the schedule from Palermo to Milan from various bus operators like FlixBus or Autoservizi Salemi for the next days.

today

$114

tomorrow

$103

Sunday

$114

Monday

$103

Tuesday

$103

Wednesday

$90

Thursday

$80

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 15m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	1:40 PM	Milan	Lampugnano Bus Station	Economy	$114	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/5/2025 3:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 1:40:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 15m
FlixBus	23h 10m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	2:35 PM	Milan	San Donato Bus Station	Economy	$142	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/5/2025 3:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/6/2025 2:35:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 23h 10m
FlixBus	25h 20m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$190	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/5/2025 5:10:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/6/2025 6:30:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 25h 20m
FlixBus	24h 0m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	5:10 PM	Milan	Lampugnano Bus Station	Economy	$199	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/5/2025 5:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 5:10:00 PM. 50 Economy ticket for $199 per person are available. Travel duration is 24h 0m

Did you know that if you travel from Palermo to Milan via Siena, you can save more than $32? You can find the corresponding connections below.
- FlixBus
  
  28h 35m
  
  0
  
  5:10 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  11:15 AM
  
  Siena
  Train Station
  
  0
  
  Economy
  
  $68
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to Train Station, Siena (Italy) arriving at 12/7/2025 11:15:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 18h 5m
- FlixBus
  
  7h 20m
  
  0
  
  2:25 PM
  
  Siena
  Train Station
  
  9:45 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 20m
Travel time is 6h 20m longer, but you will save $32

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autoservizi Salemi	19h 10m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:10 PM	Milan	San Donato Bus Station	Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 6:00:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/7/2025 1:10:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 10m
Autoservizi Salemi	19h 50m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:50 PM	Milan	Lampugnano Bus Station	Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 6:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 1:50:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 50m
FlixBus	22h 15m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	1:40 PM	Milan	Lampugnano Bus Station	Economy	$114	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 3:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 1:40:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 15m
FlixBus	24h 0m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	5:10 PM	Milan	Lampugnano Bus Station	Economy	$133	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 5:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 24h 0m
FlixBus	25h 20m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$140	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/7/2025 6:30:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 25h 20m

Did you know that if you travel from Palermo to Milan via Siena, you can save more than $21? You can find the corresponding connections below.
- FlixBus
  
  28h 35m
  
  0
  
  5:10 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  11:15 AM
  
  Siena
  Train Station
  
  0
  
  Economy
  
  $68
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to Train Station, Siena (Italy) arriving at 12/7/2025 11:15:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 18h 5m
- FlixBus
  
  7h 20m
  
  0
  
  2:25 PM
  
  Siena
  Train Station
  
  9:45 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 20m
Travel time is 9h 25m longer, but you will save $21

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 15m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	1:40 PM	Milan	Lampugnano Bus Station	Economy	$114	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/7/2025 3:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 1:40:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 15m
FlixBus	24h 45m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	5:55 PM	Milan	Lampugnano Bus Station	Economy	$160	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/7/2025 5:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 5:55:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 24h 45m
FlixBus	23h 10m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	2:35 PM	Milan	San Donato Bus Station	Economy	$166	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/7/2025 3:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/8/2025 2:35:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 23h 10m
FlixBus	25h 20m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$176	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/7/2025 5:10:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/8/2025 6:30:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 25h 20m

Did you know that if you travel from Palermo to Milan via Siena, you can save more than $32? You can find the corresponding connections below.
- FlixBus
  
  28h 35m
  
  0
  
  5:10 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  11:15 AM
  
  Siena
  Train Station
  
  0
  
  Economy
  
  $68
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to Train Station, Siena (Italy) arriving at 12/7/2025 11:15:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 18h 5m
- FlixBus
  
  7h 20m
  
  0
  
  2:25 PM
  
  Siena
  Train Station
  
  9:45 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 20m
Travel time is 6h 20m longer, but you will save $32

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autoservizi Salemi	19h 10m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:10 PM	Milan	San Donato Bus Station	Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/8/2025 6:00:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/9/2025 1:10:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 10m
Autoservizi Salemi	19h 50m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:50 PM	Milan	Lampugnano Bus Station	Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/8/2025 6:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/9/2025 1:50:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 50m
FlixBus	22h 15m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	1:40 PM	Milan	Lampugnano Bus Station	Economy	$133	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/8/2025 3:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/9/2025 1:40:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 22h 15m
FlixBus	23h 10m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	2:35 PM	Milan	San Donato Bus Station	Economy	$138	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/8/2025 3:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/9/2025 2:35:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 23h 10m
FlixBus	25h 20m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$170	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/8/2025 5:10:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/9/2025 6:30:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 25h 20m

Did you know that if you travel from Palermo to Milan via Siena, you can save more than $21? You can find the corresponding connections below.
- FlixBus
  
  28h 35m
  
  0
  
  5:10 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  11:15 AM
  
  Siena
  Train Station
  
  0
  
  Economy
  
  $68
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to Train Station, Siena (Italy) arriving at 12/7/2025 11:15:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 18h 5m
- FlixBus
  
  7h 20m
  
  0
  
  2:25 PM
  
  Siena
  Train Station
  
  9:45 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 20m
Travel time is 9h 25m longer, but you will save $21

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Autoservizi Salemi	19h 50m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:50 PM	Milan	Lampugnano Bus Station		Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/9/2025 6:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/10/2025 1:50:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 50m
	Autoservizi Salemi	19h 10m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:10 PM	Milan	San Donato Bus Station		Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/9/2025 6:00:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/10/2025 1:10:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 10m

Did you know that if you travel from Palermo to Milan via Siena, you can save more than $21? You can find the corresponding connections below.
- FlixBus
  
  28h 35m
  
  0
  
  5:10 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  11:15 AM
  
  Siena
  Train Station
  
  0
  
  Economy
  
  $68
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/6/2025 5:10:00 PM to Train Station, Siena (Italy) arriving at 12/7/2025 11:15:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 18h 5m
- FlixBus
  
  7h 20m
  
  0
  
  2:25 PM
  
  Siena
  Train Station
  
  9:45 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 20m
Travel time is 9h 25m longer, but you will save $21

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 15m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	1:40 PM	Milan	Lampugnano Bus Station	Economy	$90	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/10/2025 3:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/11/2025 1:40:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 22h 15m
FlixBus	23h 10m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	2:35 PM	Milan	San Donato Bus Station	Economy	$102	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/10/2025 3:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/11/2025 2:35:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 10m
Autoservizi Salemi	19h 10m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:10 PM	Milan	San Donato Bus Station	Basic	$105	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/10/2025 6:00:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/11/2025 1:10:00 PM. 50 Basic ticket for $105 per person are available. Travel duration is 19h 10m
Autoservizi Salemi	19h 50m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:50 PM	Milan	Lampugnano Bus Station	Basic	$105	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/10/2025 6:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/11/2025 1:50:00 PM. 50 Basic ticket for $105 per person are available. Travel duration is 19h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 15m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	1:40 PM	Milan	Lampugnano Bus Station	Economy	$80	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/11/2025 3:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 1:40:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 22h 15m
Autoservizi Salemi	19h 50m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	1:50 PM	Milan	Lampugnano Bus Station	Basic	$103	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/11/2025 6:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 1:50:00 PM. 50 Basic ticket for $103 per person are available. Travel duration is 19h 50m
FlixBus	23h 10m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	2:35 PM	Milan	San Donato Bus Station	Economy	$109	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/11/2025 3:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/12/2025 2:35:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 10m
FlixBus	24h 0m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	5:10 PM	Milan	Lampugnano Bus Station	Economy	$147	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/11/2025 5:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 5:10:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 24h 0m

Best Price Offer: The price for the cheapest bus from Palermo to Milan is $67 on 12/16/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Palermo and Milan

See here how frequent the connections between Palermo and Milan are, during different times and days of the week.

Monday is the busiest day, with more than 8 daily buses from Palermo to Milan. Tuesday has instead the fewest connections, with only 2 daily coaches between Palermo and Milan.

The busiest time of the day is the Afternoon, with 22 buses from Palermo to Milan, while Evening sees the fewest connections between Palermo and Milan, with 11 offers.

Facts about the bus from Palermo to Milan

Compare all providers like FlixBus and Autoservizi Salemi that travel 4 times every day by bus from Palermo to Milan in one click! Book your bus ticket from Palermo to Milan starting from $67!

Cheapest Bus	$67
Fastest Bus	19h 10m
Earliest Bus	3:25 PM
Latest Bus	6:00 PM
Daily Bus Routes	4 Ø
Distance	551.5 miles
Bus Companies	FlixBus and Autoservizi Salemi

Cheapest bus connections from Palermo to Milan

Every day, 4 buses from 2 bus companies leave Palermo for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$114

Saturday 12/06

$114

Sunday 12/07

$114

Monday 12/08

$133

Tuesday 12/09

$103

Wednesday 12/10

$105

Thursday 12/11

$80

Friday 12/12

$78

Saturday 12/13

$73

Sunday 12/14

$78

Monday 12/15

$78

Tuesday 12/16

$67

Wednesday 12/17

$103

Thursday 12/18

$89

Friday 12/19

$98

Saturday 12/20

$84

Sunday 12/21

$113

Monday 12/22

$115

Tuesday 12/23

$121

Wednesday 12/24

Thursday 12/25

$95

Friday 12/26

$111

Saturday 12/27

The cheapest time to travel from Palermo to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Milan, for the next 30 days.

With a price starting from $67, Tuesday is the cheapest day for a bus from Palermo to Milan. Wednesday instead is the most expensive day with prices starting from $90.

Afternoon is the cheapest day time for bus tickets from Palermo to Milan, with $80. Evening is the most expensive time of the day with prices starting from $103.

How to save money travelling from Palermo to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Palermo to Milan are also emptier.

Beloved bus companies from Palermo to Milan

These are the most booked bus companies between Palermo to Milan from our users.

Autoservizi Salemi from Palermo to Milan

Here you will find the key facts about the Autoservizi Salemi bus route Palermo to Milan:

Cheapest Price	$103
Fastest Bus	19h 10m
Earliest Bus	6:00 PM
Last Bus	6:00 PM
Daily Connections	2 Ø
Found on	12/2/2025

All bus stations and stops in Palermo and Milan

In the map below, you can see where to find all bus stations in Palermo and Milan.

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Milan? Compare all modes of transports from Palermo to Milan.

Service and Comfort on the bus from Palermo to Milan

Want to know which seat classes are available on the buses from Palermo to Milan? Or which bus companies serve the route Palermo to Milan? Below you will find answers to your questions.

FAQs about the Palermo to Milan bus

How much does a Palermo Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $67 and takes 22h 15m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Palermo to Milan?

This route is offered by 2 companies with a range of ticket prices between $67 and $199. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Palermo to Milan each day?

Every day, the Palermo to Milan bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Milan take?

The fastest bus from Palermo to Milan is offered by Autoservizi Salemi and takes 19h 10m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Milan?

The earliest bus arriving in Milan from Palermo starts at 3:25 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Milan?

The latest bus trip departing from Palermo for Milan starts at 6:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Milan route?

When traveling by bus from Palermo to Milan, passengers can travel with FlixBus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Milan?

You can check all the direct connections between Palermo and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the Palermo to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Milan on your planned travel date.

Available seat classes which are offered on the bus route Palermo to Milan

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Milan

Here’s an overview of the most popular bus routes to Palermo and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!