Bus from Palermo to Milan from $74

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Compare all timetables for the bus from Palermo to Milan

Here is a selection of the cheapest bus trips from the schedule from Palermo to Milan from various bus operators like FlixBus, Autoservizi Salemi or Sais Trasporti for the next days.

today
from $94
tomorrow
from $83
Tuesday
from $86
Wednesday
from $76
Thursday
from $74
Friday
from $81
Saturday
from $88

Cheapest bus trips today

Prices are for one way and one person
  • Autoservizi Salemi
    19h 10m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:10 PM
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    $94
  • Autoservizi Salemi
    19h 50m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:50 PM
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    $94
  • Sais Trasporti
    24h 10m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:10 PM
    Milan
    San Donato Bus Station
    0
    Sais Trasporti
    Economy
    $102
  • Sais Trasporti
    24h 55m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:55 PM
    Milan
    Lampugnano Bus Station
    0
    Sais Trasporti
    Economy
    $102
  • FlixBus
    23h 45m
    0
    9:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:55 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $122

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:40 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $83
  • Autoservizi Salemi
    19h 10m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:10 PM
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    $94
  • Autoservizi Salemi
    19h 50m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:50 PM
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    $94
  • FlixBus
    23h 10m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    2:35 PM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $101
  • FlixBus
    24h 45m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $112

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:40 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $86
  • FlixBus
    24h 45m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $143
  • FlixBus
    24h 15m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:30 PM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $146
  • FlixBus
    23h 40m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $155
  • FlixBus
    24h 20m
    0
    9:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    9:30 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $158

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:40 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $76
  • FlixBus
    24h 45m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $101
  • Autoservizi Salemi
    19h 50m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:50 PM
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    $103
  • Autoservizi Salemi
    19h 10m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:10 PM
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    $103
  • Sais Trasporti
    24h 55m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:55 PM
    Milan
    Lampugnano Bus Station
    0
    Sais Trasporti
    Economy
    $105

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:40 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    23h 10m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    2:35 PM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $100
  • Autoservizi Salemi
    19h 10m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:10 PM
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    $103
  • Autoservizi Salemi
    19h 50m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:50 PM
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    $103
  • FlixBus
    24h 5m
    0
    5:10 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:15 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $104

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:40 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $81
  • FlixBus
    23h 45m
    0
    9:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:55 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $95
  • FlixBus
    24h 45m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    24h 20m
    0
    9:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    9:30 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $97
  • FlixBus
    24h 5m
    0
    5:10 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:15 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $100

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:40 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $88
  • Autoservizi Salemi
    19h 50m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:50 PM
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    $103
  • Autoservizi Salemi
    19h 10m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    1:10 PM
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    $103
  • Sais Trasporti
    24h 55m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:55 PM
    Milan
    Lampugnano Bus Station
    0
    Sais Trasporti
    Economy
    $104
  • FlixBus
    24h 45m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $108

Frequency of bus connections between Palermo and Milan

See here how frequent the connections between Palermo and Milan are, during different times and days of the week.
Sunday is the busiest day, with more than 12 daily buses from Palermo to Milan. Tuesday has instead the fewest connections, with only 6 daily coaches between Palermo and Milan.
The busiest time of the day is the Evening, with 30 buses from Palermo to Milan, while Morning sees the fewest connections between Palermo and Milan, with 16 offers.

Facts about the bus from Palermo to Milan

Compare all providers like FlixBus, Autoservizi Salemi and Sais Trasporti that travel 8 times every day by bus from Palermo to Milan in one click! Book your bus ticket from Palermo to Milan starting from $74!

Cheapest Bus $74
Fastest Bus 19h 10m
Earliest Bus 9:10 AM
Latest Bus 6:15 PM
Daily Bus Routes 8 Ø
Distance 551.5 miles
Bus Companies FlixBus, Autoservizi Salemi and Sais Trasporti

Cheapest bus connections from Palermo to Milan

Every day, 8 buses from 3 bus companies leave Palermo for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/29/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
$122
Monday 06/30
$83
Tuesday 07/01
$86
Wednesday 07/02
$76
Thursday 07/03
$74
Friday 07/04
$81
Saturday 07/05
$88
Sunday 07/06
$103
Monday 07/07
$66
Tuesday 07/08
$71
Wednesday 07/09
$61
Thursday 07/10
$61
Friday 07/11
$76
Saturday 07/12
$76
Sunday 07/13
$69
Monday 07/14
$105
Tuesday 07/15
$99
Wednesday 07/16
$105
Thursday 07/17
$105
Friday 07/18
$90
Saturday 07/19
$105
Sunday 07/20
$115
Monday 07/21
$81
Tuesday 07/22
$94
Wednesday 07/23
$103
Thursday 07/24
$105
Friday 07/25
$90
Saturday 07/26

The cheapest time to travel from Palermo to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Milan, for the next 30 days.
With a price starting from $74, Thursday is the cheapest day for a bus from Palermo to Milan. Sunday instead is the most expensive day with prices starting from $94.
Afternoon is the cheapest day time for bus tickets from Palermo to Milan, with $74. Morning is the most expensive time of the day with prices starting from $95.

How to save money travelling from Palermo to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Palermo to Milan are also emptier.

All bus stations and stops in Palermo and Milan

In the map below, you can see where to find all bus stations in Palermo and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Milan? Compare all modes of transports from Palermo to Milan.

Service and Comfort on the bus from Palermo to Milan

Want to know which seat classes are available on the buses from Palermo to Milan? Or which bus companies serve the route Palermo to Milan? Below you will find answers to your questions.

FAQs about the Palermo to Milan bus

How much does a Palermo Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 22h 15m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Palermo to Milan?

This route is offered by 3 companies with a range of ticket prices between $74 and $187. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Palermo to Milan each day?

Every day, the Palermo to Milan bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Milan take?

The fastest bus from Palermo to Milan is offered by Autoservizi Salemi and takes 19h 10m. Bus tickets for this connection cost $94. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Milan?

The earliest bus arriving in Milan from Palermo starts at 9:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Milan?

The latest bus trip departing from Palermo for Milan starts at 6:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Milan route?

When traveling by bus from Palermo to Milan, passengers can travel with FlixBus, Autoservizi Salemi and Sais Trasporti. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Milan?

You can check all the direct connections between Palermo and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Autoservizi Salemi and Sais Trasporti.

What can I take with me on the Palermo to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Milan on your planned travel date.

Available seat classes which are offered on the bus route Palermo to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Milan

Here’s an overview of the most popular bus routes to Palermo and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Trapani to Palermo Buses Trapani to Palermo
Buses Taormina - Palermo Buses Taormina - Palermo
From Agrigento to Palermo bus From Agrigento to Palermo bus
Bus Siracusa to Palermo Bus Siracusa to Palermo
Buses from Rome to Milan Buses from Rome to Milan
Buses from Genoa to Milan Buses from Genoa to Milan
Bus Naples to Milan Bus Naples to Milan
Buses from Florence to Milan Buses from Florence to Milan
Popular Airport Shuttles to Palermo and to Milan
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