Bus Rome to Brussels: Compare prices and save money

Compare all timetables for the bus from Rome to Brussels

Here is a selection of the cheapest bus trips from the schedule from Rome to Brussels from various bus operators like FlixBus for the next days.

today

$155

tomorrow

$142

Tuesday

$140

Wednesday

$131

Thursday

Friday

$180

Saturday

$196

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	32h 25m	10:55 PM	Rome	Tiburtina Bus Station	7:20 AM	Brussels	Midi Bus Station	Economy	$155	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:55:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 7:20:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 32h 25m
FlixBus	30h 5m	5:25 PM	Rome	Anagnina Bus Station	11:30 PM	Brussels	Midi Bus Station	Economy	$160	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 5:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/22/2025 11:30:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 30h 5m
FlixBus	29h 40m	8:00 PM	Rome	Tiburtina Bus Station	1:40 AM	Brussels	Midi Bus Station	Economy	$162	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 8:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 1:40:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 29h 40m
FlixBus	27h 45m	11:50 AM	Rome	Tiburtina Bus Station	3:35 PM	Brussels	Midi Bus Station	Economy	$169	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 11:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/22/2025 3:35:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 27h 45m
FlixBus	23h 25m	12:10 PM	Rome	Tiburtina Bus Station	11:35 AM	Brussels	North Station	Economy	$172	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 12:10:00 PM to North Station, Brussels (Belgium) arriving at 12/22/2025 11:35:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 23h 25m

Did you know that if you travel from Rome to Brussels via Scandicci, you can save more than $38? You can find the corresponding connections below.
- INFOBUS
  
  22h 40m
  
  0
  
  10:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:15 PM
  
  Scandicci
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 10:00:00 AM to Bus Stop, Scandicci (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
- INFOBUS
  
  18h 25m
  
  0
  
  2:15 PM
  
  Scandicci
  Bus Stop
  
  8:40 AM
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from INFOBUS goes from Bus Stop, Scandicci (Italy) at 12/22/2025 2:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 8:40:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 25m
Travel Time is 0h 45m shorter, and you will save $38

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 25m	12:10 AM	Rome	Tiburtina Bus Station	3:35 AM	Brussels	North Station	Economy	$142	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 12:10:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 3:35:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 27h 25m
FlixBus	23h 15m	9:25 AM	Rome	Tiburtina Bus Station	8:40 AM	Brussels	North Station	Economy	$145	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 9:25:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 8:40:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 23h 15m
FlixBus	24h 55m	10:40 AM	Rome	Tiburtina Bus Station	11:35 AM	Brussels	North Station	Economy	$146	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 10:40:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 11:35:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 24h 55m
FlixBus	32h 5m	12:10 AM	Rome	Tiburtina Bus Station	8:15 AM	Brussels	Midi Bus Station	Economy	$149	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 12:10:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 8:15:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 32h 5m
FlixBus	24h 0m	8:30 AM	Rome	Tiburtina Bus Station	8:30 AM	Brussels	North Station	Economy	$155	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 8:30:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 8:30:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 24h 0m

Did you know that if you travel from Rome to Brussels via Scandicci, you can save more than $25? You can find the corresponding connections below.
- INFOBUS
  
  22h 40m
  
  0
  
  10:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:15 PM
  
  Scandicci
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 10:00:00 AM to Bus Stop, Scandicci (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
- INFOBUS
  
  18h 25m
  
  0
  
  2:15 PM
  
  Scandicci
  Bus Stop
  
  8:40 AM
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from INFOBUS goes from Bus Stop, Scandicci (Italy) at 12/22/2025 2:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 8:40:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 25m
Travel Time is 0h 35m shorter, and you will save $25

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	33h 30m	10:45 PM	Rome	Tiburtina Bus Station	8:15 AM	Brussels	Midi Bus Station	Economy	$140	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 10:45:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 8:15:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 33h 30m
FlixBus	32h 50m	11:50 PM	Rome	Tiburtina Bus Station	8:40 AM	Brussels	North Station	Economy	$147	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 11:50:00 PM to North Station, Brussels (Belgium) arriving at 12/25/2025 8:40:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 32h 50m
FlixBus	27h 25m	12:10 AM	Rome	Tiburtina Bus Station	3:35 AM	Brussels	North Station	Economy	$152	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 12:10:00 AM to North Station, Brussels (Belgium) arriving at 12/24/2025 3:35:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 27h 25m
FlixBus	29h 40m	10:10 AM	Rome	Tiburtina Bus Station	3:50 PM	Brussels	Midi Bus Station	Economy	$153	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 10:10:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 3:50:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 29h 40m
FlixBus	27h 30m	8:50 AM	Rome	Tiburtina Bus Station	12:20 PM	Brussels	Midi Bus Station	Economy	$154	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 12:20:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 27h 30m

Did you know that if you travel from Rome to Brussels via Scandicci, you can save more than $23? You can find the corresponding connections below.
- INFOBUS
  
  22h 40m
  
  0
  
  10:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:15 PM
  
  Scandicci
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 10:00:00 AM to Bus Stop, Scandicci (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
- INFOBUS
  
  18h 25m
  
  0
  
  2:15 PM
  
  Scandicci
  Bus Stop
  
  8:40 AM
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from INFOBUS goes from Bus Stop, Scandicci (Italy) at 12/22/2025 2:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 8:40:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 25m
Travel Time is 4h 45m shorter, and you will save $23

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	32h 25m	10:55 PM	Rome	Tiburtina Bus Station	7:20 AM	Brussels	Midi Bus Station	Economy	$131	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 10:55:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/26/2025 7:20:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 32h 25m
FlixBus	29h 10m	9:30 AM	Rome	Tiburtina Bus Station	2:40 PM	Brussels	North Station	Economy	$138	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 9:30:00 AM to North Station, Brussels (Belgium) arriving at 12/25/2025 2:40:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 29h 10m
FlixBus	32h 5m	12:10 AM	Rome	Tiburtina Bus Station	8:15 AM	Brussels	Midi Bus Station	Economy	$138	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 12:10:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 8:15:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 32h 5m
FlixBus	31h 45m	11:35 PM	Rome	Anagnina Bus Station	7:20 AM	Brussels	Midi Bus Station	Economy	$139	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 11:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/26/2025 7:20:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 31h 45m
FlixBus	27h 40m	1:05 PM	Rome	Anagnina Bus Station	4:45 PM	Brussels	North Station	Economy	$141	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 1:05:00 PM to North Station, Brussels (Belgium) arriving at 12/25/2025 4:45:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 27h 40m

Did you know that if you travel from Rome to Brussels via Scandicci, you can save more than $14? You can find the corresponding connections below.
- INFOBUS
  
  22h 40m
  
  0
  
  10:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:15 PM
  
  Scandicci
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 10:00:00 AM to Bus Stop, Scandicci (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
- INFOBUS
  
  18h 25m
  
  0
  
  2:15 PM
  
  Scandicci
  Bus Stop
  
  8:40 AM
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from INFOBUS goes from Bus Stop, Scandicci (Italy) at 12/22/2025 2:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 8:40:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 25m
Travel Time is 5h 0m shorter, and you will save $14

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 30m	8:50 AM	Rome	Tiburtina Bus Station	12:20 PM	Brussels	Midi Bus Station	Economy	$180	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/26/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 12:20:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 27h 30m
FlixBus	24h 55m	10:40 AM	Rome	Tiburtina Bus Station	11:35 AM	Brussels	North Station	Economy	$185	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/26/2025 10:40:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 11:35:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 24h 55m
FlixBus	32h 5m	12:10 AM	Rome	Tiburtina Bus Station	8:15 AM	Brussels	Midi Bus Station	Economy	$185	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/26/2025 12:10:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 8:15:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 32h 5m
FlixBus	23h 15m	9:25 AM	Rome	Tiburtina Bus Station	8:40 AM	Brussels	North Station	Economy	$192	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/26/2025 9:25:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 8:40:00 AM. 50 Economy ticket for $192 per person are available. Travel duration is 23h 15m
FlixBus	29h 45m	12:10 PM	Rome	Tiburtina Bus Station	5:55 PM	Brussels	Midi Bus Station	Economy	$193	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/26/2025 12:10:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 5:55:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 29h 45m

Did you know that if you travel from Rome to Brussels via Scandicci, you can save more than $63? You can find the corresponding connections below.
- INFOBUS
  
  22h 40m
  
  0
  
  10:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:15 PM
  
  Scandicci
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 10:00:00 AM to Bus Stop, Scandicci (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
- INFOBUS
  
  18h 25m
  
  0
  
  2:15 PM
  
  Scandicci
  Bus Stop
  
  8:40 AM
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from INFOBUS goes from Bus Stop, Scandicci (Italy) at 12/22/2025 2:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/23/2025 8:40:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 25m
Travel Time is 0h 35m shorter, and you will save $63

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 5m	5:25 PM	Rome	Anagnina Bus Station	11:30 PM	Brussels	Midi Bus Station	Economy	$196	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/27/2025 5:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/28/2025 11:30:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 30h 5m
FlixBus	22h 30m	10:10 AM	Rome	Tiburtina Bus Station	8:40 AM	Brussels	North Station	Economy	$197	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 10:10:00 AM to North Station, Brussels (Belgium) arriving at 12/28/2025 8:40:00 AM. 50 Economy ticket for $197 per person are available. Travel duration is 22h 30m
FlixBus	32h 25m	10:55 PM	Rome	Tiburtina Bus Station	7:20 AM	Brussels	Midi Bus Station	Economy	$203	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 10:55:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/29/2025 7:20:00 AM. 50 Economy ticket for $203 per person are available. Travel duration is 32h 25m
FlixBus	24h 25m	11:10 AM	Rome	Anagnina Bus Station	11:35 AM	Brussels	North Station	Economy	$204	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/27/2025 11:10:00 AM to North Station, Brussels (Belgium) arriving at 12/28/2025 11:35:00 AM. 50 Economy ticket for $204 per person are available. Travel duration is 24h 25m
FlixBus	31h 45m	11:35 PM	Rome	Anagnina Bus Station	7:20 AM	Brussels	Midi Bus Station	Economy	$205	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/27/2025 11:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/29/2025 7:20:00 AM. 50 Economy ticket for $205 per person are available. Travel duration is 31h 45m

Did you know that if you travel from Rome to Brussels via Scandicci, you can save more than $86? You can find the corresponding connections below.
- INFOBUS
  
  33h 0m
  
  0
  
  11:40 PM
  
  Rome
  Tiburtina Bus Station
  
  2:55 AM
  
  Scandicci
  Bus Stop
  
  0
  
  Economy
  
  $23
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 11:40:00 PM to Bus Stop, Scandicci (Italy) arriving at 12/28/2025 2:55:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 3h 15m
- INFOBUS
  
  18h 25m
  
  0
  
  2:15 PM
  
  Scandicci
  Bus Stop
  
  8:40 AM
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  $88
  
  A Bus from INFOBUS goes from Bus Stop, Scandicci (Italy) at 12/28/2025 2:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/29/2025 8:40:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 18h 25m
Travel time is 10h 30m longer, but you will save $86

Best Price Offer: The price for the cheapest bus from Rome to Brussels is $73 on 1/11/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Rome and Brussels

See here how frequent the connections between Rome and Brussels are, during different times and days of the week.

Friday is the busiest day, with more than 19 daily buses from Rome to Brussels. Sunday has instead the fewest connections, with only 11 daily coaches between Rome and Brussels.

The busiest time of the day is the Afternoon, with 34 buses from Rome to Brussels, while Night sees the fewest connections between Rome and Brussels, with 10 offers.

Facts about the bus from Rome to Brussels

Compare all providers like FlixBus that travel 16 times every day by bus from Rome to Brussels in one click! Book your bus ticket from Rome to Brussels starting from $73!

Cheapest Bus	$73
Fastest Bus	22h 30m
Earliest Bus	11:50 AM
Latest Bus	11:35 PM
Daily Bus Routes	16 Ø
Distance	729.4 miles
Bus Companies	FlixBus

Cheapest bus connections from Rome to Brussels

Every day, 16 buses from 1 bus companies leave Rome for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/21/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

$149

Monday 12/22

$142

Tuesday 12/23

$141

Wednesday 12/24

$131

Thursday 12/25

Friday 12/26

$180

Saturday 12/27

$196

Sunday 12/28

$178

Monday 12/29

$182

Tuesday 12/30

$158

Wednesday 12/31

$136

Thursday 01/01

$182

Friday 01/02

$226

Saturday 01/03

$174

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

Sunday 01/11

$73

Monday 01/12

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

Friday 01/16

Saturday 01/17

The cheapest time to travel from Rome to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Brussels, for the next 30 days.

With a price starting from $73, Sunday is the cheapest day for a bus from Rome to Brussels. Friday instead is the most expensive day with prices starting from $180.

Night is the cheapest day time for bus tickets from Rome to Brussels, with $73. Afternoon is the most expensive time of the day with prices starting from $141.

How to save money travelling from Rome to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Brussels are also emptier.

All bus stations and stops in Rome and Brussels

In the map below, you can see where to find all bus stations in Rome and Brussels.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

Central Station

Delta

PONT DU, Boulevard des Invalides, 1160 BRUXELLES, Belgium

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Brussels? Compare all modes of transports from Rome to Brussels.

Service and Comfort on the bus from Rome to Brussels

Want to know which seat classes are available on the buses from Rome to Brussels? Or which bus companies serve the route Rome to Brussels? Below you will find answers to your questions.

FAQs about the Rome to Brussels bus

How much does a Rome Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $73 and takes 32h 25m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Rome to Brussels?

This route is offered by 1 companies with a range of ticket prices between $73 and $293. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Rome to Brussels each day?

Every day, the Rome to Brussels bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Brussels take?

The fastest bus from Rome to Brussels is offered by FlixBus and takes 22h 30m. Bus tickets for this connection cost $197. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Brussels?

The earliest bus arriving in Brussels from Rome starts at 11:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Brussels?

The latest bus trip departing from Rome for Brussels starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Brussels route?

When traveling by bus from Rome to Brussels, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Brussels?

You can check all the direct connections between Rome and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 16 daily trips between Rome and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Brussels?

Prices and availability for 16 trips between Rome and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Brussels

Here’s an overview of the most popular bus routes to Rome and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!