Bus Rome to Siracusa - Compare all Companies

Compare all timetables for the bus from Rome to Siracusa

Here is a selection of the cheapest bus trips from the schedule from Rome to Siracusa from various bus operators like FlixBus for the next days.

today

tomorrow

Wednesday

Thursday

$82

Friday

Saturday

Sunday

$127

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 15m	9:00 PM	Rome	Tiburtina Bus Station	9:15 AM	Siracusa	Corso Umberto Bus Station		Economy	$82	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 4/23/2026 9:00:00 PM to Corso Umberto Bus Station, Siracusa (Italy) arriving at 4/24/2026 9:15:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 12h 15m

Did you know that if you travel from Rome to Siracusa via Catania, you can save more than $45? You can find the corresponding connections below.
- Itabus
  
  13h 5m
  
  0
  
  7:30 PM
  
  Rome
  Tiburtina Bus Station
  
  7:05 AM
  
  Catania
  Central Bus Station
  
  0
  
  Basic
  
  $30
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 4/25/2026 7:30:00 PM to Central Bus Station, Catania (Italy) arriving at 4/26/2026 7:05:00 AM. 50 Basic ticket for $30 per person are available. Travel duration is 11h 35m
- Interbus
  
  1h 2m
  
  0
  
  7:33 AM
  
  Catania
  Piazza Borsellino Bus Stop
  
  8:35 AM
  
  Siracusa
  Scala Greca Bus Station
  
  0
  
  Basic
  
  $7
  
  A Bus from Interbus goes from Piazza Borsellino Bus Stop, Catania (Italy) at 4/26/2026 7:33:00 AM to Scala Greca Bus Station, Siracusa (Italy) arriving at 4/26/2026 8:35:00 AM. 50 Basic ticket for $7 per person are available. Travel duration is 1h 2m
Travel time is 0h 50m longer, but you will save $45

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 15m	9:00 PM	Rome	Tiburtina Bus Station	9:15 AM	Siracusa	Corso Umberto Bus Station		Economy	$127	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 4/26/2026 9:00:00 PM to Corso Umberto Bus Station, Siracusa (Italy) arriving at 4/27/2026 9:15:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 12h 15m

Did you know that if you travel from Rome to Siracusa via Catania, you can save more than $99? You can find the corresponding connections below.
- Itabus
  
  17h 10m
  
  0
  
  4:25 PM
  
  Rome
  Tiburtina Bus Station
  
  8:30 AM
  
  Catania
  Central Bus Station
  
  0
  
  Premium Economy
  
  $21
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 4/25/2026 4:25:00 PM to Central Bus Station, Catania (Italy) arriving at 4/26/2026 8:30:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 16h 5m
- Interbus
  
  1h 2m
  
  0
  
  8:33 AM
  
  Catania
  Piazza Borsellino Bus Stop
  
  9:35 AM
  
  Siracusa
  Scala Greca Bus Station
  
  0
  
  Basic
  
  $7
  
  A Bus from Interbus goes from Piazza Borsellino Bus Stop, Catania (Italy) at 4/26/2026 8:33:00 AM to Scala Greca Bus Station, Siracusa (Italy) arriving at 4/26/2026 9:35:00 AM. 50 Basic ticket for $7 per person are available. Travel duration is 1h 2m
Travel time is 4h 55m longer, but you will save $99

Best Price Offer: The price for the cheapest bus from Rome to Siracusa is $42 on 5/5/2026. Flexible travelers save on ticket prices.

Facts about the bus from Rome to Siracusa

Compare all providers like FlixBus that travel 1 times every day by bus from Rome to Siracusa in one click! Book your bus ticket from Rome to Siracusa starting from $42!

Cheapest Bus	$42
Fastest Bus	12h 15m
Earliest Bus	9:00 PM
Latest Bus	9:00 PM
Daily Bus Routes	1 Ø
Distance	365.2 miles
Bus Companies	FlixBus

Cheapest bus connections from Rome to Siracusa

Every day, 1 buses from 1 bus companies leave Rome for Siracusa: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

Wednesday 04/22

Thursday 04/23

$82

Friday 04/24

Saturday 04/25

Sunday 04/26

$127

Monday 04/27

$65

Tuesday 04/28

$58

Wednesday 04/29

Thursday 04/30

$109

Friday 05/01

Saturday 05/02

$68

Sunday 05/03

$88

Monday 05/04

Tuesday 05/05

$42

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

$58

Sunday 05/10

Monday 05/11

$59

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

Friday 05/15

Saturday 05/16

How to save money travelling from Rome to Siracusa

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Siracusa in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Siracusa, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Siracusa are also emptier.

All bus stations and stops in Rome and Siracusa

In the map below, you can see where to find all bus stations in Rome and Siracusa.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Corso Umberto Bus Station

Corso Umberto 196

Scala Greca Bus Station

Viale Scala Greca 246

Corso Gelone

Corso Gelone 50

Via Von Platen

Stazione FS

Piazzale della Stazione Centrale

Service and Comfort on the bus from Rome to Siracusa

Want to know which seat classes are available on the buses from Rome to Siracusa? Or which bus companies serve the route Rome to Siracusa? Below you will find answers to your questions.

FAQs about the Rome to Siracusa bus

How much does a Rome Siracusa bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 12h 15m to reach Siracusa. Compare offers to save money!

How much could I save by comparing buses from Rome to Siracusa?

This route is offered by 1 companies with a range of ticket prices between $42 and $127. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Siracusa.

On average, how many connections are available from Rome to Siracusa each day?

Every day, the Rome to Siracusa bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Siracusa take?

The fastest bus from Rome to Siracusa is offered by FlixBus and takes 12h 15m. Bus tickets for this connection cost $82. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Siracusa?

The earliest bus arriving in Siracusa from Rome starts at 9:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Siracusa?

The latest bus trip departing from Rome for Siracusa starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Siracusa route?

When traveling by bus from Rome to Siracusa, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Siracusa?

You can check all the direct connections between Rome and Siracusa by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Siracusa bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Siracusa bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Siracusa bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Siracusa on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Siracusa?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Rome and Siracusa. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Siracusa?

Prices and availability for 1 trips between Rome and Siracusa change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Siracusa

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Siracusa

Here’s an overview of the most popular bus routes to Rome and to Siracusa. Simply click on the connection of your choice, and you will find all the details about your bus route!