Bus Santiago de Queretaro to San Diego: Compare prices and save money

Compare all timetables for the bus from Santiago de Queretaro to San Diego

Here is a selection of the cheapest bus trips from the schedule from Santiago de Queretaro to San Diego from various bus operators like Flix Mexico for the next days.

today

$220

tomorrow

$220

Wednesday

$219

Thursday

$218

Friday

Saturday

$220

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Flix Mexico	73h 40m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	10:45 PM	San Diego	San Ysidro Transit Center		Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/19/2026 11:05:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/22/2026 10:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 73h 40m
	Flix Mexico	66h 25m	7:55 PM	Santiago de Queretaro	Centro Comercial Galeria	12:20 PM	San Diego	San Ysidro Transit Center		Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/19/2026 7:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/22/2026 12:20:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 25m

Did you know that if you travel from Santiago de Queretaro to San Diego via Tijuana, BC, you can save more than $40? You can find the corresponding connections below.
- Busbud
  
  44h 35m
  
  0
  
  2:15 PM
  
  Santiago de Queretaro
  Bus Station
  
  4:20 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Bus Station, Santiago de Queretaro (Mexico) at 1/21/2026 2:15:00 PM to Central Bus Station, Tijuana, BC (Mexico) arriving at 1/23/2026 4:20:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 40h 5m
- FlixBus
  
  1h 40m
  
  0
  
  7:10 AM
  
  Tijuana, BC
  Central Bus Station
  
  8:50 AM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Tijuana, BC (Mexico) at 1/23/2026 7:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 8:50:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 40m
Travel Time is 19h 50m shorter, and you will save $40

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	73h 40m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 11:05:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 10:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 73h 40m
Flix Mexico	63h 0m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$223	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 1:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/22/2026 2:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 63h 0m
Flix Mexico	74h 0m	10:35 AM	Santiago de Queretaro	Centro Comercial Galeria	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$273	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 10:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 10:35:00 AM. 50 Economy ticket for $273 per person are available. Travel duration is 74h 0m

Did you know that if you travel from Santiago de Queretaro to San Diego via Tijuana, BC, you can save more than $40? You can find the corresponding connections below.
- Busbud
  
  44h 35m
  
  0
  
  2:15 PM
  
  Santiago de Queretaro
  Bus Station
  
  4:20 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Bus Station, Santiago de Queretaro (Mexico) at 1/21/2026 2:15:00 PM to Central Bus Station, Tijuana, BC (Mexico) arriving at 1/23/2026 4:20:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 40h 5m
- FlixBus
  
  1h 40m
  
  0
  
  7:10 AM
  
  Tijuana, BC
  Central Bus Station
  
  8:50 AM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Tijuana, BC (Mexico) at 1/23/2026 7:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 8:50:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 40m
Travel Time is 16h 25m shorter, and you will save $40

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	63h 0m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/21/2026 1:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 2:40:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 63h 0m
Flix Mexico	72h 0m	12:35 PM	Santiago de Queretaro	Centro Comercial Galeria	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/21/2026 12:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/24/2026 10:35:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 72h 0m
Flix Mexico	73h 40m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/21/2026 11:05:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/24/2026 10:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 73h 40m

Did you know that if you travel from Santiago de Queretaro to San Diego via Tijuana, BC, you can save more than $39? You can find the corresponding connections below.
- Busbud
  
  44h 35m
  
  0
  
  2:15 PM
  
  Santiago de Queretaro
  Bus Station
  
  4:20 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Bus Station, Santiago de Queretaro (Mexico) at 1/21/2026 2:15:00 PM to Central Bus Station, Tijuana, BC (Mexico) arriving at 1/23/2026 4:20:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 40h 5m
- FlixBus
  
  1h 40m
  
  0
  
  7:10 AM
  
  Tijuana, BC
  Central Bus Station
  
  8:50 AM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Tijuana, BC (Mexico) at 1/23/2026 7:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 8:50:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 40m
Travel Time is 16h 25m shorter, and you will save $39

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	73h 10m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	10:15 PM	San Diego	Seaport Village	Economy	$218	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 11:05:00 PM to Seaport Village, San Diego (USA) arriving at 1/25/2026 10:15:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 73h 10m
Flix Mexico	68h 40m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	5:45 PM	San Diego	Old Town Transit Center	Economy	$218	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 11:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 1/25/2026 5:45:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 68h 40m
Flix Mexico	70h 35m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	10:15 PM	San Diego	Seaport Village	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 1:40:00 AM to Seaport Village, San Diego (USA) arriving at 1/24/2026 10:15:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 70h 35m
Flix Mexico	64h 40m	7:55 PM	Santiago de Queretaro	Centro Comercial Galeria	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 7:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/25/2026 10:35:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 64h 40m
Flix Mexico	73h 40m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 11:05:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/25/2026 10:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 73h 40m

Did you know that if you travel from Santiago de Queretaro to San Diego via Tijuana, BC, you can save more than $38? You can find the corresponding connections below.
- Busbud
  
  44h 35m
  
  0
  
  2:15 PM
  
  Santiago de Queretaro
  Bus Station
  
  4:20 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Bus Station, Santiago de Queretaro (Mexico) at 1/21/2026 2:15:00 PM to Central Bus Station, Tijuana, BC (Mexico) arriving at 1/23/2026 4:20:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 40h 5m
- FlixBus
  
  1h 40m
  
  0
  
  7:10 AM
  
  Tijuana, BC
  Central Bus Station
  
  8:50 AM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Tijuana, BC (Mexico) at 1/23/2026 7:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 8:50:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 40m
Travel Time is 18h 5m shorter, and you will save $38

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	73h 40m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 11:05:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/27/2026 10:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 73h 40m
Flix Mexico	66h 25m	7:55 PM	Santiago de Queretaro	Centro Comercial Galeria	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 7:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/27/2026 12:20:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 25m
Flix Mexico	71h 15m	7:55 PM	Santiago de Queretaro	Centro Comercial Galeria	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$223	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 7:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 1/27/2026 5:10:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 71h 15m
Flix Mexico	63h 0m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$229	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 1:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/26/2026 2:40:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 63h 0m
Flix Mexico	65h 30m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$230	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 1:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/26/2026 5:10:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 65h 30m

Did you know that if you travel from Santiago de Queretaro to San Diego via Tijuana, BC, you can save more than $40? You can find the corresponding connections below.
- Busbud
  
  44h 35m
  
  0
  
  2:15 PM
  
  Santiago de Queretaro
  Bus Station
  
  4:20 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Bus Station, Santiago de Queretaro (Mexico) at 1/21/2026 2:15:00 PM to Central Bus Station, Tijuana, BC (Mexico) arriving at 1/23/2026 4:20:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 40h 5m
- FlixBus
  
  1h 40m
  
  0
  
  7:10 AM
  
  Tijuana, BC
  Central Bus Station
  
  8:50 AM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Tijuana, BC (Mexico) at 1/23/2026 7:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 1/23/2026 8:50:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 40m
Travel Time is 16h 25m shorter, and you will save $40

Best Price Offer: The price for the cheapest bus from Santiago de Queretaro to San Diego is $218 on 1/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago de Queretaro and San Diego

See here how frequent the connections between Santiago de Queretaro and San Diego are, during different times and days of the week.

Thursday is the busiest day, with more than 13 daily buses from Santiago de Queretaro to San Diego. Monday has instead the fewest connections, with only 2 daily coaches between Santiago de Queretaro and San Diego.

The busiest time of the day is the Evening, with 15 buses from Santiago de Queretaro to San Diego, while Morning sees the fewest connections between Santiago de Queretaro and San Diego, with 1 offers.

Facts about the bus from Santiago de Queretaro to San Diego

Compare all providers like Flix Mexico that travel 5 times every day by bus from Santiago de Queretaro to San Diego in one click! Book your bus ticket from Santiago de Queretaro to San Diego starting from $218!

Cheapest Bus	$218
Fastest Bus	60h 30m
Earliest Bus	7:55 PM
Latest Bus	11:05 PM
Daily Bus Routes	5 Ø
Distance	1,331.0 miles
Bus Companies	Flix Mexico

Cheapest bus connections from Santiago de Queretaro to San Diego

Every day, 5 buses from 1 bus companies leave Santiago de Queretaro for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$220

Tuesday 01/20

$220

Wednesday 01/21

$219

Thursday 01/22

$218

Friday 01/23

Saturday 01/24

$220

Sunday 01/25

Monday 01/26

$220

Tuesday 01/27

$219

Wednesday 01/28

Thursday 01/29

$220

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Santiago de Queretaro to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago de Queretaro to San Diego, for the next 30 days.

With a price starting from $218, Thursday is the cheapest day for a bus from Santiago de Queretaro to San Diego. Monday instead is the most expensive day with prices starting from $220.

Afternoon is the cheapest day time for bus tickets from Santiago de Queretaro to San Diego, with $218. Morning is the most expensive time of the day with prices starting from $271.

How to save money travelling from Santiago de Queretaro to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago de Queretaro to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago de Queretaro to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago de Queretaro to San Diego are also emptier.

All bus stations and stops in Santiago de Queretaro and San Diego

In the map below, you can see where to find all bus stations in Santiago de Queretaro and San Diego.

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Santiago de Queretaro to San Diego

Want to know which seat classes are available on the buses from Santiago de Queretaro to San Diego? Or which bus companies serve the route Santiago de Queretaro to San Diego? Below you will find answers to your questions.

FAQs about the Santiago de Queretaro to San Diego bus

How much does a Santiago de Queretaro San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $218 and takes 66h 40m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Santiago de Queretaro to San Diego?

This route is offered by 1 companies with a range of ticket prices between $218 and $273. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Santiago de Queretaro to San Diego each day?

Every day, the Santiago de Queretaro to San Diego bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago de Queretaro to San Diego take?

The fastest bus from Santiago de Queretaro to San Diego is offered by Flix Mexico and takes 60h 30m. Bus tickets for this connection cost $236. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago de Queretaro to San Diego?

The earliest bus arriving in San Diego from Santiago de Queretaro starts at 7:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago de Queretaro to San Diego?

The latest bus trip departing from Santiago de Queretaro for San Diego starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago de Queretaro San Diego route?

When traveling by bus from Santiago de Queretaro to San Diego, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago de Queretaro and San Diego?

You can check all the direct connections between Santiago de Queretaro and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Santiago de Queretaro to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago de Queretaro San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago de Queretaro San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago de Queretaro to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago de Queretaro to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Santiago de Queretaro and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago de Queretaro to San Diego?

Prices and availability for 5 trips between Santiago de Queretaro and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago de Queretaro to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santiago de Queretaro and to San Diego

Here’s an overview of the most popular bus routes to Santiago de Queretaro and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!