Bus Santiago de Queretaro to San Diego: Compare prices and save money

Compare all timetables for the bus from Santiago de Queretaro to San Diego

Here is a selection of the cheapest bus trips from the schedule from Santiago de Queretaro to San Diego from various bus operators like Flix Mexico for the next days.

today

$217

tomorrow

$216

Thursday

Friday

Saturday

$220

Sunday

Monday

$215

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	64h 40m	1:30 AM	Santiago de Queretaro	Centro Comercial Galeria	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$217	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 7/21/2026 1:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 7/23/2026 5:10:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 64h 40m
Flix Mexico	68h 25m	10:55 PM	Santiago de Queretaro	Centro Comercial Galeria	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$225	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 7/21/2026 10:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 7/24/2026 6:20:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 68h 25m
Flix Mexico	69h 50m	3:30 PM	Santiago de Queretaro	Centro Comercial Galeria	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$239	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 7/21/2026 3:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 7/24/2026 12:20:00 PM. 50 Economy ticket for $239 per person are available. Travel duration is 69h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	63h 55m	1:30 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$216	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/22/2026 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/24/2026 4:25:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 63h 55m
Flix Mexico	69h 45m	1:30 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$219	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/22/2026 1:30:00 AM to Seaport Village, San Diego (USA) arriving at 7/24/2026 10:15:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 69h 45m
Flix Mexico	67h 50m	10:55 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	5:45 PM	San Diego	Old Town Transit Center	Economy	$221	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/22/2026 10:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/25/2026 5:45:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 67h 50m
Flix Mexico	72h 20m	10:55 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$224	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/22/2026 10:55:00 PM to Seaport Village, San Diego (USA) arriving at 7/25/2026 10:15:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 72h 20m
Flix Mexico	65h 15m	1:30 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	5:45 PM	San Diego	Old Town Transit Center	Economy	$224	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/22/2026 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/24/2026 5:45:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 65h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	65h 15m	1:30 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	5:45 PM	San Diego	Old Town Transit Center	Economy	$220	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/25/2026 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/27/2026 5:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 65h 15m
Flix Mexico	67h 50m	10:55 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	5:45 PM	San Diego	Old Town Transit Center	Economy	$220	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/25/2026 10:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/28/2026 5:45:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 67h 50m
Flix Mexico	70h 55m	6:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$222	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/25/2026 6:30:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/28/2026 4:25:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 70h 55m
Flix Mexico	66h 15m	6:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$222	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/25/2026 6:30:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/28/2026 11:45:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 66h 15m
Flix Mexico	66h 50m	6:30 PM	Santiago de Queretaro	Centro Comercial Galeria	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$223	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 7/25/2026 6:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 7/28/2026 12:20:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 66h 50m

Did you know that if you travel from Santiago de Queretaro to San Diego via Tijuana, BC, you can save more than $22? You can find the corresponding connections below.
- Elite Select
  
  41h 17m
  
  0
  
  4:33 PM
  
  Santiago de Queretaro
  Terminal Norte
  
  7:09 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  0
  
  Economy
  
  $195
  
  A Bus from Elite Select goes from Terminal Norte, Santiago de Queretaro (Mexico) at 7/26/2026 4:33:00 PM to Centro Bus Stop, Tijuana, BC (Mexico) arriving at 7/28/2026 7:09:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 39h 36m
- Greyhound US
  
  1h 40m
  
  0
  
  7:10 AM
  
  Tijuana, BC
  Central Bus Station
  
  8:50 AM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $4
  
  A Bus from Greyhound US goes from Central Bus Station, Tijuana, BC (Mexico) at 7/28/2026 7:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 7/28/2026 8:50:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 1h 40m
Travel Time is 22h 58m shorter, and you will save $22

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	72h 20m	10:55 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$215	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/27/2026 10:55:00 PM to Seaport Village, San Diego (USA) arriving at 7/30/2026 10:15:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 72h 20m
Flix Mexico	63h 55m	1:30 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$215	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/27/2026 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/29/2026 4:25:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 63h 55m
Flix Mexico	67h 50m	10:55 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	5:45 PM	San Diego	Old Town Transit Center	Economy	$216	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/27/2026 10:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/30/2026 5:45:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 67h 50m
Flix Mexico	69h 45m	1:30 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$219	A Bus from Flix Mexico goes from Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) at 7/27/2026 1:30:00 AM to Seaport Village, San Diego (USA) arriving at 7/29/2026 10:15:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 69h 45m
Flix Mexico	64h 40m	1:30 AM	Santiago de Queretaro	Centro Comercial Galeria	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 7/27/2026 1:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 7/29/2026 5:10:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 64h 40m

Best Price Offer: The price for the cheapest bus from Santiago de Queretaro to San Diego is $215 on 7/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago de Queretaro and San Diego

See here how frequent the connections between Santiago de Queretaro and San Diego are, during different times and days of the week.

Monday is the busiest day, with more than 10 daily buses from Santiago de Queretaro to San Diego. Tuesday has instead the fewest connections, with only 3 daily coaches between Santiago de Queretaro and San Diego.

The busiest time of the day is the Evening, with 15 buses from Santiago de Queretaro to San Diego, while Afternoon sees the fewest connections between Santiago de Queretaro and San Diego, with 4 offers.

Facts about the bus from Santiago de Queretaro to San Diego

Compare all providers like Flix Mexico that travel 7 times every day by bus from Santiago de Queretaro to San Diego in one click! Book your bus ticket from Santiago de Queretaro to San Diego starting from $215!

Cheapest Bus	$215
Fastest Bus	62h 55m
Earliest Bus	1:30 AM
Latest Bus	10:55 PM
Daily Bus Routes	7 Ø
Distance	1,331.0 miles
Bus Companies	Flix Mexico

Cheapest bus connections from Santiago de Queretaro to San Diego

Every day, 7 buses from 1 bus companies leave Santiago de Queretaro for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

$217

Wednesday 07/22

$216

Thursday 07/23

Friday 07/24

Saturday 07/25

$220

Sunday 07/26

Monday 07/27

$215

Tuesday 07/28

$218

Wednesday 07/29

$221

Thursday 07/30

$216

Friday 07/31

$218

Saturday 08/01

$222

Sunday 08/02

$219

Monday 08/03

$218

Tuesday 08/04

$216

Wednesday 08/05

$222

Thursday 08/06

$216

Friday 08/07

$219

Saturday 08/08

$218

Sunday 08/09

$218

Monday 08/10

$216

Tuesday 08/11

$221

Wednesday 08/12

$216

Thursday 08/13

Friday 08/14

$216

Saturday 08/15

The cheapest time to travel from Santiago de Queretaro to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago de Queretaro to San Diego, for the next 30 days.

With a price starting from $215, Monday is the cheapest day for a bus from Santiago de Queretaro to San Diego. Saturday instead is the most expensive day with prices starting from $218.

Night is the cheapest day time for bus tickets from Santiago de Queretaro to San Diego, with $215. Afternoon is the most expensive time of the day with prices starting from $231.

How to save money travelling from Santiago de Queretaro to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago de Queretaro to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago de Queretaro to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago de Queretaro to San Diego are also emptier.

All bus stations and stops in Santiago de Queretaro and San Diego

In the map below, you can see where to find all bus stations in Santiago de Queretaro and San Diego.

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Seaport Village

W Harbor Dr 789

Santa Fe Depot

Kettner Blvd 1050

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Santiago de Queretaro to San Diego

Want to know which seat classes are available on the buses from Santiago de Queretaro to San Diego? Or which bus companies serve the route Santiago de Queretaro to San Diego? Below you will find answers to your questions.

FAQs about the Santiago de Queretaro to San Diego bus

How much does a Santiago de Queretaro San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $215 and takes 62h 55m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Santiago de Queretaro to San Diego?

This route is offered by 1 companies with a range of ticket prices between $215 and $239. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Santiago de Queretaro to San Diego each day?

Every day, the Santiago de Queretaro to San Diego bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago de Queretaro to San Diego take?

The fastest bus from Santiago de Queretaro to San Diego is offered by Flix Mexico and takes 62h 55m. Bus tickets for this connection cost $216. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago de Queretaro to San Diego?

The earliest bus arriving in San Diego from Santiago de Queretaro starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago de Queretaro to San Diego?

The latest bus trip departing from Santiago de Queretaro for San Diego starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago de Queretaro San Diego route?

When traveling by bus from Santiago de Queretaro to San Diego, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago de Queretaro and San Diego?

You can check all the direct connections between Santiago de Queretaro and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Santiago de Queretaro to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago de Queretaro San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago de Queretaro San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago de Queretaro to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago de Queretaro to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Santiago de Queretaro and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago de Queretaro to San Diego?

Prices and availability for 7 trips between Santiago de Queretaro and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago de Queretaro to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santiago de Queretaro and to San Diego

Here’s an overview of the most popular bus routes to Santiago de Queretaro and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!