Bus St. Louis, MO to Charlotte: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Charlotte

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Charlotte from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Friday

$131

Saturday

Sunday

$146

Monday

Tuesday

$150

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$131	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/19/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/20/2025 9:05:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 18h 20m
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$131	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/19/2025 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 12/20/2025 11:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 18h 30m
FlixBus	17h 30m	11:30 PM	St. Louis, MO	Gateway Station	6:00 PM	Charlotte	Freedom Drive 3301	Economy	$131	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/19/2025 11:30:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 12/20/2025 6:00:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 17h 30m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$132	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/19/2025 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/19/2025 11:50:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 21h 50m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$132	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/19/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/19/2025 11:35:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 21h 35m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$146	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/21/2025 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 12/22/2025 11:30:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 18h 30m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$152	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/21/2025 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/21/2025 11:50:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 21h 50m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$153	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/21/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/21/2025 11:35:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 21h 35m
FlixBus	17h 50m	11:30 PM	St. Louis, MO	Gateway Station	6:20 PM	Charlotte	W Trade St	Economy	$155	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/21/2025 11:30:00 PM to W Trade St, Charlotte (USA) arriving at 12/22/2025 6:20:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 17h 50m
FlixBus	17h 30m	11:30 PM	St. Louis, MO	Gateway Station	6:00 PM	Charlotte	Freedom Drive 3301	Economy	$156	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/21/2025 11:30:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 12/22/2025 6:00:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 17h 30m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 0m	1:55 PM	St. Louis, MO	Gateway Station	11:55 AM	Charlotte	W Trade St	Economy	$150	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/23/2025 1:55:00 PM to W Trade St, Charlotte (USA) arriving at 12/24/2025 11:55:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 21h 0m
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$152	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/23/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/24/2025 9:05:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 18h 20m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$157	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/23/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/23/2025 11:35:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 35m
FlixBus	19h 50m	4:00 PM	St. Louis, MO	Gateway Station	12:50 PM	Charlotte	W Trade St	Economy	$160	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/23/2025 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 12/24/2025 12:50:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 19h 50m
FlixBus	17h 50m	11:30 PM	St. Louis, MO	Gateway Station	6:20 PM	Charlotte	W Trade St	Economy	$175	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/23/2025 11:30:00 PM to W Trade St, Charlotte (USA) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 17h 50m

Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $17? You can find the corresponding connections below.
- Busbud
  
  18h 20m
  
  0
  
  1:45 PM
  
  St. Louis, MO
  Gateway Station
  
  9:00 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $45
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 12/20/2025 1:45:00 PM to 5th Ave South Station, Nashville (USA) arriving at 12/20/2025 9:00:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 7h 15m
- FlixBus
  
  10h 20m
  
  0
  
  9:45 PM
  
  Nashville
  5th Ave South Station
  
  9:05 AM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $88
  
  A Bus from FlixBus goes from 5th Ave South Station, Nashville (USA) at 12/20/2025 9:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/21/2025 9:05:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 10h 20m
Travel Time is 0h 30m shorter, and you will save $17

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Charlotte is $113 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Charlotte

See here how frequent the connections between St. Louis, MO and Charlotte are, during different times and days of the week.

Friday is the busiest day, with more than 14 daily buses from St. Louis, MO to Charlotte. Sunday has instead the fewest connections, with only 7 daily coaches between St. Louis, MO and Charlotte.

The busiest time of the day is the Night, with 12 buses from St. Louis, MO to Charlotte, while Evening sees the fewest connections between St. Louis, MO and Charlotte, with 8 offers.

Facts about the bus from St. Louis, MO to Charlotte

Compare all providers like Greyhound US and FlixBus that travel 9 times every day by bus from St. Louis, MO to Charlotte in one click! Book your bus ticket from St. Louis, MO to Charlotte starting from $113!

Cheapest Bus	$113
Fastest Bus	18h 30m
Earliest Bus	1:00 AM
Latest Bus	11:30 PM
Daily Bus Routes	9 Ø
Distance	567.1 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Charlotte

Every day, 9 buses from 2 bus companies leave St. Louis, MO for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$131

Saturday 12/20

Sunday 12/21

$146

Monday 12/22

Tuesday 12/23

$150

Wednesday 12/24

Thursday 12/25

$121

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

$137

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from St. Louis, MO to Charlotte

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Charlotte, for the next 30 days.

With a price starting from $131, Friday is the cheapest day for a bus from St. Louis, MO to Charlotte. Tuesday instead is the most expensive day with prices starting from $150.

Night is the cheapest day time for bus tickets from St. Louis, MO to Charlotte, with $121. Evening is the most expensive time of the day with prices starting from $131.

How to save money travelling from St. Louis, MO to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Charlotte are also emptier.

Beloved bus companies from St. Louis, MO to Charlotte

These are the most booked bus companies between St. Louis, MO to Charlotte from our users.

Greyhound US from St. Louis, MO to Charlotte

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to Charlotte:

Cheapest Price	$131
Fastest Bus	19h 20m
Earliest Bus	1:00 AM
Last Bus	1:55 PM
Daily Connections	5 Ø
Found on	12/14/2025

FlixBus from St. Louis, MO to Charlotte

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Charlotte:

Cheapest Price	$131
Fastest Bus	18h 30m
Earliest Bus	4:00 PM
Last Bus	11:30 PM
Daily Connections	4 Ø
Found on	12/14/2025

All bus stations and stops in St. Louis, MO and Charlotte

In the map below, you can see where to find all bus stations in St. Louis, MO and Charlotte.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Church St

S Church St 330

Arrowood Light Rail Station

South Blvd 7430

Service and Comfort on the bus from St. Louis, MO to Charlotte

Want to know which seat classes are available on the buses from St. Louis, MO to Charlotte? Or which bus companies serve the route St. Louis, MO to Charlotte? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Charlotte bus

How much does a St. Louis, MO Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $113 and takes 19h 20m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $113 and $180. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from St. Louis, MO to Charlotte each day?

Every day, the St. Louis, MO to Charlotte bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Charlotte take?

The fastest bus from St. Louis, MO to Charlotte is offered by FlixBus and takes 18h 30m. Bus tickets for this connection cost $135. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Charlotte?

The earliest bus arriving in Charlotte from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Charlotte?

The latest bus trip departing from St. Louis, MO for Charlotte starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Charlotte route?

When traveling by bus from St. Louis, MO to Charlotte, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Charlotte?

You can check all the direct connections between St. Louis, MO and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Charlotte on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Charlotte?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between St. Louis, MO and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Charlotte?

Prices and availability for 9 trips between St. Louis, MO and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Charlotte

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Charlotte

Here’s an overview of the most popular bus routes to St. Louis, MO and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!