Bus St. Louis, MO to Charlotte: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Charlotte

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Charlotte from various bus operators like Greyhound US or FlixBus for the next days.

today

$112

tomorrow

$108

Sunday

Monday

$119

Tuesday

Wednesday

$122

Thursday

$126

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$112	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/5/2025 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/5/2025 11:50:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 21h 50m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$112	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/5/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/5/2025 11:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 21h 35m
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$112	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/5/2025 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 12/6/2025 11:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 18h 30m
FlixBus	17h 50m	11:30 PM	St. Louis, MO	Gateway Station	6:20 PM	Charlotte	W Trade St	Economy	$112	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/5/2025 11:30:00 PM to W Trade St, Charlotte (USA) arriving at 12/6/2025 6:20:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 17h 50m
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$114	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/5/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/6/2025 9:05:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 18h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 0m	2:00 AM	St. Louis, MO	Gateway Station	5:00 AM	Charlotte	W Trade St	Economy	$108	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 2:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/7/2025 5:00:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 26h 0m
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$108	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 12/7/2025 11:30:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 30m
FlixBus	17h 50m	11:30 PM	St. Louis, MO	Gateway Station	6:20 PM	Charlotte	W Trade St	Economy	$108	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 11:30:00 PM to W Trade St, Charlotte (USA) arriving at 12/7/2025 6:20:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 17h 50m
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$109	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/7/2025 9:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 18h 20m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$109	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/6/2025 11:35:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 21h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 25m	11:30 PM	St. Louis, MO	Gateway Station	8:55 PM	Charlotte	W Trade St	Economy	$119	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 11:30:00 PM to W Trade St, Charlotte (USA) arriving at 12/9/2025 8:55:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 20h 25m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$120	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/8/2025 11:50:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 21h 50m
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$120	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/9/2025 9:05:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 18h 20m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$120	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/8/2025 11:35:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 21h 35m
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$120	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 12/9/2025 11:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 18h 30m

Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $12? You can find the corresponding connections below.
- Busbud
  
  18h 20m
  
  0
  
  1:45 PM
  
  St. Louis, MO
  Gateway Station
  
  9:00 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $37
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:45:00 PM to 5th Ave South Station, Nashville (USA) arriving at 12/8/2025 9:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 15m
- FlixBus
  
  10h 20m
  
  0
  
  9:45 PM
  
  Nashville
  5th Ave South Station
  
  9:05 AM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $70
  
  A Bus from FlixBus goes from 5th Ave South Station, Nashville (USA) at 12/8/2025 9:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/9/2025 9:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 20m
Travel Time is 1h 0m shorter, and you will save $12

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$122	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/10/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/11/2025 9:05:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 18h 20m
Greyhound US	21h 0m	1:55 PM	St. Louis, MO	Gateway Station	11:55 AM	Charlotte	W Trade St	Economy	$122	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/10/2025 1:55:00 PM to W Trade St, Charlotte (USA) arriving at 12/11/2025 11:55:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 21h 0m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$125	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/10/2025 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/10/2025 11:50:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 21h 50m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$126	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/10/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/10/2025 11:35:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 21h 35m
Greyhound US	26h 0m	2:00 AM	St. Louis, MO	Gateway Station	5:00 AM	Charlotte	W Trade St	Economy	$138	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/10/2025 2:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/11/2025 5:00:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 26h 0m

Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $15? You can find the corresponding connections below.
- Busbud
  
  18h 20m
  
  0
  
  1:45 PM
  
  St. Louis, MO
  Gateway Station
  
  9:00 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $37
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:45:00 PM to 5th Ave South Station, Nashville (USA) arriving at 12/8/2025 9:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 15m
- FlixBus
  
  10h 20m
  
  0
  
  9:45 PM
  
  Nashville
  5th Ave South Station
  
  9:05 AM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $70
  
  A Bus from FlixBus goes from 5th Ave South Station, Nashville (USA) at 12/8/2025 9:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/9/2025 9:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 20m
Travel Time is 1h 0m shorter, and you will save $15

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 50m	11:30 PM	St. Louis, MO	Gateway Station	6:20 PM	Charlotte	W Trade St	Economy	$126	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/11/2025 11:30:00 PM to W Trade St, Charlotte (USA) arriving at 12/12/2025 6:20:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 17h 50m
FlixBus	17h 30m	11:30 PM	St. Louis, MO	Gateway Station	6:00 PM	Charlotte	Freedom Drive 3301	Economy	$128	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/11/2025 11:30:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 12/12/2025 6:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 17h 30m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$131	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/11/2025 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 12/11/2025 11:50:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 21h 50m
Greyhound US	18h 20m	1:45 PM	St. Louis, MO	Gateway Station	9:05 AM	Charlotte	W Trade St	Economy	$131	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/11/2025 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/12/2025 9:05:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 18h 20m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$132	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/11/2025 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 12/11/2025 11:35:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 21h 35m

Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $19? You can find the corresponding connections below.
- Busbud
  
  18h 20m
  
  0
  
  1:45 PM
  
  St. Louis, MO
  Gateway Station
  
  9:00 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $37
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:45:00 PM to 5th Ave South Station, Nashville (USA) arriving at 12/8/2025 9:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 15m
- FlixBus
  
  10h 20m
  
  0
  
  9:45 PM
  
  Nashville
  5th Ave South Station
  
  9:05 AM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $70
  
  A Bus from FlixBus goes from 5th Ave South Station, Nashville (USA) at 12/8/2025 9:45:00 PM to W Trade St, Charlotte (USA) arriving at 12/9/2025 9:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 20m
Travel Time is 0h 10m shorter, and you will save $19

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Charlotte is $101 on 12/4/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Charlotte

See here how frequent the connections between St. Louis, MO and Charlotte are, during different times and days of the week.

Monday is the busiest day, with more than 14 daily buses from St. Louis, MO to Charlotte. Wednesday has instead the fewest connections, with only 6 daily coaches between St. Louis, MO and Charlotte.

The busiest time of the day is the Night, with 24 buses from St. Louis, MO to Charlotte, while Evening sees the fewest connections between St. Louis, MO and Charlotte, with 14 offers.

Facts about the bus from St. Louis, MO to Charlotte

Compare all providers like Greyhound US and FlixBus that travel 11 times every day by bus from St. Louis, MO to Charlotte in one click! Book your bus ticket from St. Louis, MO to Charlotte starting from $101!

Cheapest Bus	$101
Fastest Bus	18h 30m
Earliest Bus	1:00 AM
Latest Bus	11:30 PM
Daily Bus Routes	11 Ø
Distance	567.1 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Charlotte

Every day, 11 buses from 2 bus companies leave St. Louis, MO for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$117

Saturday 12/06

$119

Sunday 12/07

Monday 12/08

$119

Tuesday 12/09

Wednesday 12/10

$122

Thursday 12/11

$126

Friday 12/12

$126

Saturday 12/13

$136

Sunday 12/14

$118

Monday 12/15

$113

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$131

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

$121

Friday 12/26

Saturday 12/27

The cheapest time to travel from St. Louis, MO to Charlotte

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Charlotte, for the next 30 days.

With a price starting from $108, Saturday is the cheapest day for a bus from St. Louis, MO to Charlotte. Wednesday instead is the most expensive day with prices starting from $122.

Afternoon is the cheapest day time for bus tickets from St. Louis, MO to Charlotte, with $108. Evening is the most expensive time of the day with prices starting from $108.

How to save money travelling from St. Louis, MO to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Charlotte are also emptier.

Beloved bus companies from St. Louis, MO to Charlotte

These are the most booked bus companies between St. Louis, MO to Charlotte from our users.

Greyhound US from St. Louis, MO to Charlotte

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to Charlotte:

Cheapest Price	$108
Fastest Bus	19h 20m
Earliest Bus	1:00 AM
Last Bus	1:45 PM
Daily Connections	6 Ø
Found on	12/3/2025

FlixBus from St. Louis, MO to Charlotte

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Charlotte:

Cheapest Price	$108
Fastest Bus	18h 30m
Earliest Bus	4:00 PM
Last Bus	11:30 PM
Daily Connections	5 Ø
Found on	12/3/2025

All bus stations and stops in St. Louis, MO and Charlotte

In the map below, you can see where to find all bus stations in St. Louis, MO and Charlotte.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Church St

S Church St 330

Arrowood Light Rail Station

South Blvd 7430

Service and Comfort on the bus from St. Louis, MO to Charlotte

Want to know which seat classes are available on the buses from St. Louis, MO to Charlotte? Or which bus companies serve the route St. Louis, MO to Charlotte? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Charlotte bus

How much does a St. Louis, MO Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $101 and takes 27h 0m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $101 and $138. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from St. Louis, MO to Charlotte each day?

Every day, the St. Louis, MO to Charlotte bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Charlotte take?

The fastest bus from St. Louis, MO to Charlotte is offered by FlixBus and takes 18h 30m. Bus tickets for this connection cost $114. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Charlotte?

The earliest bus arriving in Charlotte from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Charlotte?

The latest bus trip departing from St. Louis, MO for Charlotte starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Charlotte route?

When traveling by bus from St. Louis, MO to Charlotte, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Charlotte?

You can check all the direct connections between St. Louis, MO and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Charlotte on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to Charlotte

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Charlotte

Here’s an overview of the most popular bus routes to St. Louis, MO and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!