Bus from St. Louis, MO to Charlotte from $85

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Compare all timetables for the bus from St. Louis, MO to Charlotte

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Charlotte from various bus operators like Greyhound US or FlixBus for the next days.

today
tomorrow
Friday
Saturday
$167
Sunday
Monday
Tuesday
$157

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 50m 1:00 AM St. Louis, MO Gateway Station 11:50 PM Charlotte W Trade St  Economy $167
Greyhound US 26h 0m 2:00 AM St. Louis, MO Gateway Station 5:00 AM Charlotte W Trade St  Economy $167
Greyhound US 18h 20m 1:45 PM St. Louis, MO Gateway Station 9:05 AM Charlotte W Trade St  Economy $168
FlixBus 17h 30m 11:30 PM St. Louis, MO Gateway Station 6:00 PM Charlotte Freedom Drive 3301  Economy $168
FlixBus 18h 30m 4:00 PM St. Louis, MO Gateway Station 11:30 AM Charlotte W Trade St  Economy $169
  • Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $63? You can find the corresponding connections below.
    • Busbud
      18h 20m
      0
      1:45 PM
      St. Louis, MO
      Gateway Station
      9:00 PM
      Nashville
      5th Ave South Station
      0
      Busbud
      Economy
      $36
      • Waiting Time 0h 45m
    • FlixBus
      10h 20m
      0
      9:45 PM
      Nashville
      5th Ave South Station
      9:05 AM
      Charlotte
      W Trade St
      0
      FlixBus
      Economy
      $68
    Travel Time is 0h 10m shorter, and you will save $63

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 18h 20m 1:45 PM St. Louis, MO Gateway Station 9:05 AM Charlotte W Trade St  Economy $157
Greyhound US 21h 50m 1:00 AM St. Louis, MO Gateway Station 11:50 PM Charlotte W Trade St  Economy $158
Greyhound US 26h 0m 2:00 AM St. Louis, MO Gateway Station 5:00 AM Charlotte W Trade St  Economy $158
FlixBus 20h 25m 11:30 PM St. Louis, MO Gateway Station 8:55 PM Charlotte W Trade St  Economy $159
FlixBus 23h 5m 11:30 PM St. Louis, MO Gateway Station 11:35 PM Charlotte Freedom Drive 3301  Economy $159
  • Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $53? You can find the corresponding connections below.
    • Busbud
      18h 20m
      0
      1:45 PM
      St. Louis, MO
      Gateway Station
      9:00 PM
      Nashville
      5th Ave South Station
      0
      Busbud
      Economy
      $36
      • Waiting Time 0h 45m
    • FlixBus
      10h 20m
      0
      9:45 PM
      Nashville
      5th Ave South Station
      9:05 AM
      Charlotte
      W Trade St
      0
      FlixBus
      Economy
      $68
    Travel Time is 1h 0m shorter, and you will save $53

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Charlotte is $85 on 2/16/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between St. Louis, MO and Charlotte

See here how frequent the connections between St. Louis, MO and Charlotte are, during different times and days of the week.
Tuesday is the busiest day, with more than 7 daily buses from St. Louis, MO to Charlotte. Tuesday has instead the fewest connections, with only 7 daily coaches between St. Louis, MO and Charlotte.
The busiest time of the day is the Night, with 6 buses from St. Louis, MO to Charlotte, while Afternoon sees the fewest connections between St. Louis, MO and Charlotte, with 4 offers.

Facts about the bus from St. Louis, MO to Charlotte

Compare all providers like Greyhound US and FlixBus that travel 7 times every day by bus from St. Louis, MO to Charlotte in one click! Book your bus ticket from St. Louis, MO to Charlotte starting from $85!

Cheapest Bus $85
Fastest Bus 18h 30m
Earliest Bus 1:00 AM
Latest Bus 11:30 PM
Daily Bus Routes 7 Ø
Distance 567.1 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Charlotte

Every day, 7 buses from 2 bus companies leave St. Louis, MO for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/04/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$167
Sunday 02/08
Monday 02/09
Tuesday 02/10
$157
Wednesday 02/11
$172
Thursday 02/12
Friday 02/13
Saturday 02/14
$96
Sunday 02/15
Monday 02/16
$85
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
$130
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

The cheapest time to travel from St. Louis, MO to Charlotte

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Charlotte, for the next 30 days.
With a price starting from $96, Saturday is the cheapest day for a bus from St. Louis, MO to Charlotte. Tuesday instead is the most expensive day with prices starting from $157.
Night is the cheapest day time for bus tickets from St. Louis, MO to Charlotte, with $85. Evening is the most expensive time of the day with prices starting from $159.

How to save money travelling from St. Louis, MO to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Charlotte are also emptier.

Beloved bus companies from St. Louis, MO to Charlotte

These are the most booked bus companies between St. Louis, MO to Charlotte from our users.

FlixBus from St. Louis, MO to Charlotte

FlixBus

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Charlotte:

Cheapest Price $159
Fastest Bus 18h 30m
Earliest Bus 4:00 PM
Last Bus 11:30 PM
Daily Connections 2 Ø
Found on 2/1/2026

All bus stations and stops in St. Louis, MO and Charlotte

In the map below, you can see where to find all bus stations in St. Louis, MO and Charlotte.

Service and Comfort on the bus from St. Louis, MO to Charlotte

Want to know which seat classes are available on the buses from St. Louis, MO to Charlotte? Or which bus companies serve the route St. Louis, MO to Charlotte? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Charlotte bus

How much does a St. Louis, MO Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $85 and takes 19h 20m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $85 and $169. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from St. Louis, MO to Charlotte each day?

Every day, the St. Louis, MO to Charlotte bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Charlotte take?

The fastest bus from St. Louis, MO to Charlotte is offered by FlixBus and takes 18h 30m. Bus tickets for this connection cost $168. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Charlotte?

The earliest bus arriving in Charlotte from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Charlotte?

The latest bus trip departing from St. Louis, MO for Charlotte starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Charlotte route?

When traveling by bus from St. Louis, MO to Charlotte, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Charlotte?

You can check all the direct connections between St. Louis, MO and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Charlotte on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Charlotte?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between St. Louis, MO and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Charlotte?

Prices and availability for 7 trips between St. Louis, MO and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Charlotte

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Charlotte

Here’s an overview of the most popular bus routes to St. Louis, MO and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to St. Louis, MO and to Charlotte
CheckMyBus › Buses in USA › Bus to St. Louis, MO › Bus to Charlotte

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