Bus St. Louis, MO to Charlotte: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Charlotte

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Charlotte from various bus operators like Greyhound US or FlixBus for the next days.

today

$137

tomorrow

$127

Monday

Tuesday

Wednesday

Thursday

Friday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 0m	2:00 AM	St. Louis, MO	Gateway Station	5:00 AM	Charlotte	W Trade St	Economy	$137	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/21/2026 2:00:00 AM to W Trade St, Charlotte (USA) arriving at 3/22/2026 5:00:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 26h 0m
FlixBus	25h 0m	4:00 PM	St. Louis, MO	Gateway Station	6:00 PM	Charlotte	Freedom Drive 3301	Economy	$137	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 3/21/2026 4:00:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 3/22/2026 6:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 25h 0m
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$138	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 3/21/2026 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 3/22/2026 11:30:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 18h 30m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$153	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/21/2026 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 3/21/2026 11:50:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 21h 50m
Greyhound US	21h 35m	1:00 AM	St. Louis, MO	Gateway Station	11:35 PM	Charlotte	Freedom Drive 3301	Economy	$154	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/21/2026 1:00:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 3/21/2026 11:35:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 21h 35m

Did you know that if you travel from St. Louis, MO to Charlotte via Nashville, you can save more than $22? You can find the corresponding connections below.
- Greyhound US
  
  23h 5m
  
  0
  
  1:55 PM
  
  St. Louis, MO
  Gateway Station
  
  1:25 AM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $42
  
  A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/22/2026 1:55:00 PM to 5th Ave South Station, Nashville (USA) arriving at 3/23/2026 1:25:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 11h 30m
- Greyhound US
  
  10h 10m
  
  0
  
  2:50 AM
  
  Nashville
  5th Ave South Station
  
  2:00 PM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $72
  
  A Bus from Greyhound US goes from 5th Ave South Station, Nashville (USA) at 3/23/2026 2:50:00 AM to W Trade St, Charlotte (USA) arriving at 3/23/2026 2:00:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 10h 10m
Travel time is 3h 35m longer, but you will save $22

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	1:45 PM	St. Louis, MO	Gateway Station	8:40 AM	Charlotte	W Trade St	Economy	$127	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/22/2026 1:45:00 PM to W Trade St, Charlotte (USA) arriving at 3/23/2026 8:40:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 17h 55m
FlixBus	18h 30m	4:00 PM	St. Louis, MO	Gateway Station	11:30 AM	Charlotte	W Trade St	Economy	$127	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 3/22/2026 4:00:00 PM to W Trade St, Charlotte (USA) arriving at 3/23/2026 11:30:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 18h 30m
Greyhound US	26h 0m	2:00 AM	St. Louis, MO	Gateway Station	5:00 AM	Charlotte	W Trade St	Economy	$128	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/22/2026 2:00:00 AM to W Trade St, Charlotte (USA) arriving at 3/23/2026 5:00:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 26h 0m
FlixBus	25h 0m	4:00 PM	St. Louis, MO	Gateway Station	6:00 PM	Charlotte	Freedom Drive 3301	Economy	$128	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 3/22/2026 4:00:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 3/23/2026 6:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m
Greyhound US	21h 50m	1:00 AM	St. Louis, MO	Gateway Station	11:50 PM	Charlotte	W Trade St	Economy	$144	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 3/22/2026 1:00:00 AM to W Trade St, Charlotte (USA) arriving at 3/22/2026 11:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 21h 50m

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Charlotte is $81 on 4/6/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Charlotte

See here how frequent the connections between St. Louis, MO and Charlotte are, during different times and days of the week.

Sunday is the busiest day, with more than 12 daily buses from St. Louis, MO to Charlotte. Sunday has instead the fewest connections, with only 12 daily coaches between St. Louis, MO and Charlotte.

The busiest time of the day is the Afternoon, with 12 buses from St. Louis, MO to Charlotte, while Afternoon sees the fewest connections between St. Louis, MO and Charlotte, with 12 offers.

Facts about the bus from St. Louis, MO to Charlotte

Compare all providers like Greyhound US and FlixBus that travel 12 times every day by bus from St. Louis, MO to Charlotte in one click! Book your bus ticket from St. Louis, MO to Charlotte starting from $81!

Cheapest Bus	$81
Fastest Bus	18h 55m
Earliest Bus	1:00 AM
Latest Bus	4:00 PM
Daily Bus Routes	12 Ø
Distance	567.1 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Charlotte

Every day, 12 buses from 2 bus companies leave St. Louis, MO for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/15

Monday 03/16

Tuesday 03/17

Wednesday 03/18

Thursday 03/19

Friday 03/20

Saturday 03/21

$137

Sunday 03/22

$128

Monday 03/23

Tuesday 03/24

Wednesday 03/25

Thursday 03/26

Friday 03/27

Saturday 03/28

$92

Sunday 03/29

$92

Monday 03/30

Tuesday 03/31

Wednesday 04/01

$100

Thursday 04/02

Friday 04/03

Saturday 04/04

$92

Sunday 04/05

$86

Monday 04/06

$81

Tuesday 04/07

$98

Wednesday 04/08

Thursday 04/09

$84

Friday 04/10

Saturday 04/11

The cheapest time to travel from St. Louis, MO to Charlotte

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Charlotte, for the next 30 days.

With a price starting from $86, Sunday is the cheapest day for a bus from St. Louis, MO to Charlotte. Saturday instead is the most expensive day with prices starting from $92.

Night is the cheapest day time for bus tickets from St. Louis, MO to Charlotte, with $81. Afternoon is the most expensive time of the day with prices starting from $127.

How to save money travelling from St. Louis, MO to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Charlotte are also emptier.

All bus stations and stops in St. Louis, MO and Charlotte

In the map below, you can see where to find all bus stations in St. Louis, MO and Charlotte.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Arrowood Light Rail Station

South Blvd 7430

Church St

S Church St 330

Service and Comfort on the bus from St. Louis, MO to Charlotte

Want to know which seat classes are available on the buses from St. Louis, MO to Charlotte? Or which bus companies serve the route St. Louis, MO to Charlotte? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Charlotte bus

How much does a St. Louis, MO Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $81 and takes 18h 55m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $81 and $159. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from St. Louis, MO to Charlotte each day?

Every day, the St. Louis, MO to Charlotte bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Charlotte take?

The fastest bus from St. Louis, MO to Charlotte is offered by Greyhound US and takes 18h 55m. Bus tickets for this connection cost $159. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Charlotte?

The earliest bus arriving in Charlotte from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Charlotte?

The latest bus trip departing from St. Louis, MO for Charlotte starts at 4:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Charlotte route?

When traveling by bus from St. Louis, MO to Charlotte, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Charlotte?

You can check all the direct connections between St. Louis, MO and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Charlotte on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Charlotte?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between St. Louis, MO and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Charlotte?

Prices and availability for 12 trips between St. Louis, MO and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Charlotte

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Charlotte

Here’s an overview of the most popular bus routes to St. Louis, MO and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!