Bus from Knoxville, TN to Fort Pierce, FL from $144

Compare all the bus companies and find the best price with CheckMyBus
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Knoxville, TN to Fort Pierce, FL

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Fort Pierce, FL from various bus operators like Greyhound US for the next days.

today
$144
tomorrow
Sunday
Monday
$150
Tuesday
Wednesday
Thursday
$145

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 32h 50m 6:10 PM Knoxville, TN Greyhound Bus Station 3:00 AM Fort Pierce, FL Okeechobee Road  Economy $144
Greyhound US 19h 40m 7:05 PM Knoxville, TN Greyhound Bus Station 2:45 PM Fort Pierce, FL Greyhound Bus Station  Economy $145

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 40m 7:05 PM Knoxville, TN Greyhound Bus Station 2:45 PM Fort Pierce, FL Greyhound Bus Station  Economy $150
Greyhound US 30h 50m 7:05 PM Knoxville, TN Greyhound Bus Station 1:55 AM Fort Pierce, FL Okeechobee Road  Economy $173
  • Did you know that if you travel from Knoxville, TN to Fort Pierce, FL via Atlanta, GA, you can save more than $21? You can find the corresponding connections below.
    • FlixBus
      19h 40m
      0
      7:05 PM
      Knoxville, TN
      Greyhound Bus Station
      11:00 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $37
    • Waiting Time 1h 50m
    • FlixBus
      13h 55m
      0
      12:50 AM
      Atlanta, GA
      Garnett Transit Station
      2:45 PM
      Fort Pierce, FL
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $92
    Travel time is the same as the direct connection, but you will save $21

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 45m 6:10 PM Knoxville, TN Greyhound Bus Station 1:55 AM Fort Pierce, FL Okeechobee Road  Economy $145
Greyhound US 19h 40m 7:05 PM Knoxville, TN Greyhound Bus Station 2:45 PM Fort Pierce, FL Greyhound Bus Station  Economy $145
  • Did you know that if you travel from Knoxville, TN to Fort Pierce, FL via Atlanta, GA, you can save more than $36? You can find the corresponding connections below.
    • FlixBus
      24h 55m
      0
      7:05 PM
      Knoxville, TN
      Greyhound Bus Station
      11:00 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $37
    • Waiting Time 7h 30m
    • FlixBus
      13h 30m
      0
      6:30 AM
      Atlanta, GA
      Garnett Transit Station
      8:00 PM
      Fort Pierce, FL
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $72
    Travel time is 5h 15m longer, but you will save $36

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Fort Pierce, FL is $144 on 12/5/2025. Flexible travelers save on ticket prices.


Facts about the bus from Knoxville, TN to Fort Pierce, FL

Compare all providers like Greyhound US that travel 2 times every day by bus from Knoxville, TN to Fort Pierce, FL in one click! Book your bus ticket from Knoxville, TN to Fort Pierce, FL starting from $144!

Cheapest Bus $144
Fastest Bus 19h 40m
Earliest Bus 6:10 PM
Latest Bus 7:05 PM
Daily Bus Routes 2 Ø
Distance 625.3 miles
Bus Companies Greyhound US

Cheapest bus connections from Knoxville, TN to Fort Pierce, FL

Every day, 2 buses from 1 bus companies leave Knoxville, TN for Fort Pierce, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
$144
Saturday 12/06
Sunday 12/07
Monday 12/08
$150
Tuesday 12/09
Wednesday 12/10
Thursday 12/11
$145
Friday 12/12
Saturday 12/13
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

How to save money travelling from Knoxville, TN to Fort Pierce, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Fort Pierce, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Fort Pierce, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Fort Pierce, FL are also emptier.

All bus stations and stops in Knoxville, TN and Fort Pierce, FL

In the map below, you can see where to find all bus stations in Knoxville, TN and Fort Pierce, FL.

Service and Comfort on the bus from Knoxville, TN to Fort Pierce, FL

Want to know which seat classes are available on the buses from Knoxville, TN to Fort Pierce, FL? Or which bus companies serve the route Knoxville, TN to Fort Pierce, FL? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Fort Pierce, FL bus

How much does a Knoxville, TN Fort Pierce, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $144 and takes 32h 50m to reach Fort Pierce, FL. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Fort Pierce, FL?

This route is offered by 1 companies with a range of ticket prices between $144 and $173. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Fort Pierce, FL.

On average, how many connections are available from Knoxville, TN to Fort Pierce, FL each day?

Every day, the Knoxville, TN to Fort Pierce, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Fort Pierce, FL take?

The fastest bus from Knoxville, TN to Fort Pierce, FL is offered by Greyhound US and takes 19h 40m. Bus tickets for this connection cost $145. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Fort Pierce, FL?

The earliest bus arriving in Fort Pierce, FL from Knoxville, TN starts at 6:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Fort Pierce, FL?

The latest bus trip departing from Knoxville, TN for Fort Pierce, FL starts at 7:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Fort Pierce, FL route?

When traveling by bus from Knoxville, TN to Fort Pierce, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Fort Pierce, FL?

You can check all the direct connections between Knoxville, TN and Fort Pierce, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Fort Pierce, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Fort Pierce, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Fort Pierce, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Fort Pierce, FL on your planned travel date.

Available seat classes which are offered on the bus route Knoxville, TN to Fort Pierce, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Fort Pierce, FL

Here’s an overview of the most popular bus routes to Knoxville, TN and to Fort Pierce, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.