Bus Louisville, KY to San Antonio, TX

Compare all timetables for the bus from Louisville, KY to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Louisville, KY to San Antonio, TX from various bus operators like Greyhound US for the next days.

today

$110

tomorrow

$137

Thursday

Friday

$120

Saturday

Sunday

$109

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 0m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/3/2026 1:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/4/2026 12:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 24h 0m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/3/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/4/2026 6:10:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 24h 40m
Greyhound US	26h 10m	10:55 PM	Louisville, KY	Greyhound Bus Station	12:05 AM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/3/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/5/2026 12:05:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 26h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 35m	3:35 AM	Louisville, KY	Greyhound Bus Station	5:10 AM	San Antonio, TX	Bus Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/4/2026 3:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 11/5/2026 5:10:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 26h 35m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/4/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/5/2026 6:10:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 24h 40m
Greyhound US	26h 10m	10:55 PM	Louisville, KY	Greyhound Bus Station	12:05 AM	San Antonio, TX	Bus Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/4/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/6/2026 12:05:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 26h 10m
Greyhound US	46h 30m	10:55 PM	Louisville, KY	Greyhound Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$138	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/4/2026 10:55:00 PM to Pearl District, San Antonio, TX (USA) arriving at 11/6/2026 8:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 46h 30m
Greyhound US	24h 0m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$151	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/4/2026 1:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/5/2026 12:55:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 24h 0m

Did you know that if you travel from Louisville, KY to San Antonio, TX via Austin, you can save more than $26? You can find the corresponding connections below.
- Greyhound US
  
  22h 55m
  
  0
  
  7:15 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  3:25 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  0
  
  Economy
  
  $98
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/6/2026 7:15:00 AM to 5119 Eastside Bus Plaza, Austin (USA) arriving at 11/7/2026 3:25:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 21h 10m
- Greyhound US
  
  1h 30m
  
  0
  
  3:40 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:10 AM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Greyhound US goes from 5119 Eastside Bus Plaza, Austin (USA) at 11/7/2026 3:40:00 AM to Bus Station, San Antonio, TX (USA) arriving at 11/7/2026 5:10:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 30m
Travel Time is 0h 5m shorter, and you will save $26

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 55m	7:15 AM	Louisville, KY	Greyhound Bus Station	5:10 AM	San Antonio, TX	Bus Station	Economy	$120	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/6/2026 7:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 11/7/2026 5:10:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 22h 55m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$120	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/6/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/7/2026 6:10:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 24h 40m
Greyhound US	26h 10m	10:55 PM	Louisville, KY	Greyhound Bus Station	12:05 AM	San Antonio, TX	Bus Station	Economy	$120	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/6/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/8/2026 12:05:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 26h 10m
Greyhound US	36h 50m	8:35 AM	Louisville, KY	Greyhound Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$121	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/6/2026 8:35:00 AM to Pearl District, San Antonio, TX (USA) arriving at 11/7/2026 8:25:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 36h 50m
Greyhound US	24h 0m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$122	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/6/2026 1:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/7/2026 12:55:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 24h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	35h 25m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:20 AM	San Antonio, TX	Pearl District	Economy	$109	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/8/2026 1:55:00 PM to Pearl District, San Antonio, TX (USA) arriving at 11/10/2026 12:20:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 35h 25m
Greyhound US	24h 0m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/8/2026 1:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/9/2026 12:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 24h 0m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/8/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/9/2026 6:10:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 24h 40m
Greyhound US	26h 10m	10:55 PM	Louisville, KY	Greyhound Bus Station	12:05 AM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/8/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 11/10/2026 12:05:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 26h 10m
Greyhound US	22h 55m	7:15 AM	Louisville, KY	Greyhound Bus Station	5:10 AM	San Antonio, TX	Bus Station	Economy	$113	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 11/8/2026 7:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 11/9/2026 5:10:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 22h 55m

Best Price Offer: The price for the cheapest bus from Louisville, KY to San Antonio, TX is $107 on 11/18/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Louisville, KY and San Antonio, TX

See here how frequent the connections between Louisville, KY and San Antonio, TX are, during different times and days of the week.

Wednesday is the busiest day, with more than 10 daily buses from Louisville, KY to San Antonio, TX. Tuesday has instead the fewest connections, with only 3 daily coaches between Louisville, KY and San Antonio, TX.

The busiest time of the day is the Evening, with 12 buses from Louisville, KY to San Antonio, TX, while Night sees the fewest connections between Louisville, KY and San Antonio, TX, with 2 offers.

Facts about the bus from Louisville, KY to San Antonio, TX

Compare all providers like Greyhound US that travel 6 times every day by bus from Louisville, KY to San Antonio, TX in one click! Book your bus ticket from Louisville, KY to San Antonio, TX starting from $107!

Cheapest Bus	$107
Fastest Bus	21h 55m
Earliest Bus	1:55 PM
Latest Bus	10:55 PM
Daily Bus Routes	6 Ø
Distance	949.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Louisville, KY to San Antonio, TX

Every day, 6 buses from 1 bus companies leave Louisville, KY for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/01

Monday 11/02

Tuesday 11/03

$110

Wednesday 11/04

$108

Thursday 11/05

Friday 11/06

$120

Saturday 11/07

Sunday 11/08

$109

Monday 11/09

Tuesday 11/10

$113

Wednesday 11/11

Thursday 11/12

Friday 11/13

Saturday 11/14

$116

Sunday 11/15

Monday 11/16

$124

Tuesday 11/17

$117

Wednesday 11/18

$107

Thursday 11/19

$137

Friday 11/20

$151

Saturday 11/21

Sunday 11/22

Monday 11/23

Tuesday 11/24

Wednesday 11/25

Thursday 11/26

$155

Friday 11/27

Saturday 11/28

The cheapest time to travel from Louisville, KY to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Louisville, KY to San Antonio, TX, for the next 30 days.

With a price starting from $107, Wednesday is the cheapest day for a bus from Louisville, KY to San Antonio, TX. Friday instead is the most expensive day with prices starting from $120.

Night is the cheapest day time for bus tickets from Louisville, KY to San Antonio, TX, with $107. Morning is the most expensive time of the day with prices starting from $113.

How to save money travelling from Louisville, KY to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Louisville, KY to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to San Antonio, TX are also emptier.

Beloved bus companies from Louisville, KY to San Antonio, TX

These are the most booked bus companies between Louisville, KY to San Antonio, TX from our users.

Greyhound US from Louisville, KY to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route Louisville, KY to San Antonio, TX:

Cheapest Price	$109
Fastest Bus	21h 55m
Earliest Bus	1:55 PM
Last Bus	10:55 PM
Daily Connections	6 Ø
Found on	10/21/2026

All bus stations and stops in Louisville, KY and San Antonio, TX

In the map below, you can see where to find all bus stations in Louisville, KY and San Antonio, TX.

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Bus Station

N St Mary's St 500

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Urban Loop

East Campus Bus Stop

Service and Comfort on the bus from Louisville, KY to San Antonio, TX

Want to know which seat classes are available on the buses from Louisville, KY to San Antonio, TX? Or which bus companies serve the route Louisville, KY to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Louisville, KY to San Antonio, TX bus

How much does a Louisville, KY San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 34h 25m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Louisville, KY to San Antonio, TX?

This route is offered by 1 companies with a range of ticket prices between $107 and $155. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Louisville, KY to San Antonio, TX each day?

Every day, the Louisville, KY to San Antonio, TX bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Louisville, KY to San Antonio, TX take?

The fastest bus from Louisville, KY to San Antonio, TX is offered by Greyhound US and takes 21h 55m. Bus tickets for this connection cost $120. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Louisville, KY to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Louisville, KY starts at 1:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Louisville, KY to San Antonio, TX?

The latest bus trip departing from Louisville, KY for San Antonio, TX starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Louisville, KY San Antonio, TX route?

When traveling by bus from Louisville, KY to San Antonio, TX, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Louisville, KY and San Antonio, TX?

You can check all the direct connections between Louisville, KY and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Louisville, KY to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Louisville, KY San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Louisville, KY San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Louisville, KY to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Louisville, KY to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Louisville, KY and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Louisville, KY to San Antonio, TX?

Prices and availability for 6 trips between Louisville, KY and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Louisville, KY to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Louisville, KY and to San Antonio, TX

Here’s an overview of the most popular bus routes to Louisville, KY and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!