Bus Milwaukee to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Milwaukee to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Milwaukee to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today

$49

tomorrow

$54

Thursday

$54

Friday

Saturday

$59

Sunday

Monday

$54

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	11h 20m	11:55 AM	Milwaukee	Central Bus Station	11:15 PM	St. Louis, MO	Gateway Station		Economy	$49	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 10/27/2026 11:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/27/2026 11:15:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 11h 20m
	Greyhound US	11h 25m	8:30 PM	Milwaukee	Central Bus Station	7:55 AM	St. Louis, MO	Gateway Station		Economy	$52	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/27/2026 8:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 10/28/2026 7:55:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 25m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	9h 50m	8:30 PM	Milwaukee	Central Bus Station	6:20 AM	St. Louis, MO	Gateway Station		Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/28/2026 8:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 10/29/2026 6:20:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 9h 50m
	Greyhound US	16h 45m	6:30 AM	Milwaukee	Central Bus Station	11:15 PM	St. Louis, MO	Gateway Station		Economy	$59	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/28/2026 6:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/28/2026 11:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 16h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	14h 15m	9:00 AM	Milwaukee	Central Bus Station	11:15 PM	St. Louis, MO	Gateway Station	Economy	$54	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 10/29/2026 9:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/29/2026 11:15:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 15m
Greyhound US	9h 50m	8:30 PM	Milwaukee	Central Bus Station	6:20 AM	St. Louis, MO	Gateway Station	Economy	$56	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/29/2026 8:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 10/30/2026 6:20:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 9h 50m
Greyhound US	9h 10m	6:30 AM	Milwaukee	Central Bus Station	3:40 PM	St. Louis, MO	Gateway Station	Economy	$59	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/29/2026 6:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/29/2026 3:40:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 9h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	9h 50m	8:30 PM	Milwaukee	Central Bus Station	5:20 AM	St. Louis, MO	Gateway Station	Economy	$59	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/31/2026 8:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 11/1/2026 5:20:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 9h 50m
FlixBus	11h 25m	11:50 AM	Milwaukee	Central Bus Station	11:15 PM	St. Louis, MO	Gateway Station	Economy	$59	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 10/31/2026 11:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/31/2026 11:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 11h 25m
Greyhound US	9h 10m	6:30 AM	Milwaukee	Central Bus Station	3:40 PM	St. Louis, MO	Gateway Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/31/2026 6:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/31/2026 3:40:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 10m

Did you know that if you travel from Milwaukee to St. Louis, MO via Chicago, you can save more than $8? You can find the corresponding connections below.
- Greyhound US
  
  9h 50m
  
  0
  
  8:30 PM
  
  Milwaukee
  Central Bus Station
  
  10:05 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $12
  
  A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 10/28/2026 8:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/28/2026 10:05:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 35m
- FlixBus
  
  5h 40m
  
  0
  
  12:40 AM
  
  Chicago
  95th Red Line Station
  
  6:20 AM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $39
  
  A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 10/29/2026 12:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 10/29/2026 6:20:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 5h 40m
Travel time is 1h 0m longer, but you will save $8

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 25m	11:50 AM	Milwaukee	Central Bus Station	11:15 PM	St. Louis, MO	Gateway Station	Economy	$54	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 11/2/2026 11:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 11/2/2026 11:15:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 25m
Greyhound US	9h 10m	6:30 AM	Milwaukee	Central Bus Station	3:40 PM	St. Louis, MO	Gateway Station	Economy	$62	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 11/2/2026 6:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 11/2/2026 3:40:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 9h 10m
Greyhound US	11h 25m	8:30 PM	Milwaukee	Central Bus Station	7:55 AM	St. Louis, MO	Gateway Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 11/2/2026 8:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 11/3/2026 7:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 11h 25m

Best Price Offer: The price for the cheapest bus from Milwaukee to St. Louis, MO is $44 on 11/3/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milwaukee and St. Louis, MO

See here how frequent the connections between Milwaukee and St. Louis, MO are, during different times and days of the week.

Saturday is the busiest day, with more than 6 daily buses from Milwaukee to St. Louis, MO. Wednesday has instead the fewest connections, with only 2 daily coaches between Milwaukee and St. Louis, MO.

The busiest time of the day is the Morning, with 11 buses from Milwaukee to St. Louis, MO, while Evening sees the fewest connections between Milwaukee and St. Louis, MO, with 7 offers.

Facts about the bus from Milwaukee to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from Milwaukee to St. Louis, MO in one click! Book your bus ticket from Milwaukee to St. Louis, MO starting from $44!

Cheapest Bus	$44
Fastest Bus	8h 50m
Earliest Bus	11:55 AM
Latest Bus	8:30 PM
Daily Bus Routes	3 Ø
Distance	327.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Milwaukee to St. Louis, MO

Every day, 3 buses from 2 bus companies leave Milwaukee for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/25

Monday 10/26

Tuesday 10/27

$49

Wednesday 10/28

$54

Thursday 10/29

$54

Friday 10/30

Saturday 10/31

$62

Sunday 11/01

Monday 11/02

$54

Tuesday 11/03

$44

Wednesday 11/04

$51

Thursday 11/05

$47

Friday 11/06

Saturday 11/07

$53

Sunday 11/08

$59

Monday 11/09

Tuesday 11/10

$51

Wednesday 11/11

$52

Thursday 11/12

$56

Friday 11/13

Saturday 11/14

$64

Sunday 11/15

$60

Monday 11/16

$62

Tuesday 11/17

$63

Wednesday 11/18

$50

Thursday 11/19

$63

Friday 11/20

$79

Saturday 11/21

The cheapest time to travel from Milwaukee to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Milwaukee to St. Louis, MO, for the next 30 days.

With a price starting from $44, Tuesday is the cheapest day for a bus from Milwaukee to St. Louis, MO. Monday instead is the most expensive day with prices starting from $54.

Morning is the cheapest day time for bus tickets from Milwaukee to St. Louis, MO, with $49. Evening is the most expensive time of the day with prices starting from $52.

How to save money travelling from Milwaukee to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milwaukee to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milwaukee to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milwaukee to St. Louis, MO are also emptier.

All bus stations and stops in Milwaukee and St. Louis, MO

In the map below, you can see where to find all bus stations in Milwaukee and St. Louis, MO.

Intermodal Station

W. St Paul's Ave 433

4960 S. 13th St. Park

Badger

N James Lovell St 635

Downtown Bus Station

S84 & Adler

S84 & Oconnor #6533

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Gateway Station

S 15th St 430

Service and Comfort on the bus from Milwaukee to St. Louis, MO

Want to know which seat classes are available on the buses from Milwaukee to St. Louis, MO? Or which bus companies serve the route Milwaukee to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Milwaukee to St. Louis, MO bus

How much does a Milwaukee St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $44 and takes 11h 20m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Milwaukee to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $44 and $78. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Milwaukee to St. Louis, MO each day?

Every day, the Milwaukee to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milwaukee to St. Louis, MO take?

The fastest bus from Milwaukee to St. Louis, MO is offered by Greyhound US and takes 8h 50m. Bus tickets for this connection cost $59. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milwaukee to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Milwaukee starts at 11:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milwaukee to St. Louis, MO?

The latest bus trip departing from Milwaukee for St. Louis, MO starts at 8:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milwaukee St. Louis, MO route?

When traveling by bus from Milwaukee to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milwaukee and St. Louis, MO?

You can check all the direct connections between Milwaukee and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Milwaukee to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milwaukee St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milwaukee St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milwaukee to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Milwaukee to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Milwaukee and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milwaukee to St. Louis, MO?

Prices and availability for 3 trips between Milwaukee and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milwaukee to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milwaukee and to St. Louis, MO

Here’s an overview of the most popular bus routes to Milwaukee and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!