Bus San Luis Potosí to San Diego: Compare prices and save money

Compare all timetables for the bus from San Luis Potosí to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Luis Potosí to San Diego from various bus operators like Flix Mexico for the next days.

today

$216

tomorrow

$216

Wednesday

Thursday

Friday

$215

Saturday

$221

Sunday

$220

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	69h 5m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$216	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/4/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/7/2026 6:10:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 69h 5m
Flix Mexico	62h 25m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$219	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/4/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/6/2026 11:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 62h 25m
Flix Mexico	60h 50m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$219	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/4/2026 10:25:00 AM to Seaport Village, San Diego (USA) arriving at 5/6/2026 10:15:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 60h 50m
Flix Mexico	73h 10m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$219	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/4/2026 10:05:00 PM to Seaport Village, San Diego (USA) arriving at 5/7/2026 10:15:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 73h 10m
Flix Mexico	62h 10m	5:00 AM	San Luis Potosí	Soriana El Paseo Bus Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$222	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/4/2026 5:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/6/2026 6:10:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 62h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	55h 0m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$216	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/5/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/7/2026 4:25:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 55h 0m
Flix Mexico	80h 25m	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$217	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/5/2026 2:50:00 PM to Seaport Village, San Diego (USA) arriving at 5/8/2026 10:15:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 80h 25m
Flix Mexico	60h 50m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$219	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/5/2026 10:25:00 AM to Seaport Village, San Diego (USA) arriving at 5/7/2026 10:15:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 60h 50m
Flix Mexico	62h 25m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$219	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/5/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/7/2026 11:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 62h 25m
Flix Mexico	74h 35m	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$226	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/5/2026 2:50:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/8/2026 4:25:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 74h 35m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	60h 50m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$215	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/8/2026 10:25:00 AM to Seaport Village, San Diego (USA) arriving at 5/10/2026 10:15:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 60h 50m
Flix Mexico	55h 0m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$215	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/8/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/10/2026 4:25:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 55h 0m
Flix Mexico	56h 20m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$216	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/8/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/10/2026 5:45:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 56h 20m
Flix Mexico	67h 20m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$217	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/8/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/11/2026 4:25:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 67h 20m
Flix Mexico	62h 40m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$218	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/8/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/11/2026 11:45:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 62h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	73h 10m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$221	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/9/2026 10:05:00 PM to Seaport Village, San Diego (USA) arriving at 5/12/2026 10:15:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 73h 10m
Flix Mexico	54h 30m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$223	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/9/2026 10:25:00 AM to La Jolla Village, San Diego (USA) arriving at 5/11/2026 3:55:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 54h 30m
Flix Mexico	60h 50m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$224	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/9/2026 10:25:00 AM to Seaport Village, San Diego (USA) arriving at 5/11/2026 10:15:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 60h 50m
Flix Mexico	55h 0m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$224	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/9/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/11/2026 4:25:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 55h 0m
Flix Mexico	56h 20m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$224	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/9/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/11/2026 5:45:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 56h 20m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	73h 10m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$220	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/10/2026 10:05:00 PM to Seaport Village, San Diego (USA) arriving at 5/13/2026 10:15:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 73h 10m
Flix Mexico	62h 40m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$222	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/10/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/13/2026 11:45:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 62h 40m
Flix Mexico	54h 30m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$223	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/10/2026 10:25:00 AM to La Jolla Village, San Diego (USA) arriving at 5/12/2026 3:55:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 54h 30m
Flix Mexico	55h 0m	10:25 AM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$224	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/10/2026 10:25:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/12/2026 4:25:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 55h 0m
Flix Mexico	67h 20m	10:05 PM	San Luis Potosí	Soriana El Paseo Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$224	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 5/10/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/13/2026 4:25:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 67h 20m

Best Price Offer: The price for the cheapest bus from San Luis Potosí to San Diego is $215 on 5/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Luis Potosí and San Diego

See here how frequent the connections between San Luis Potosí and San Diego are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily buses from San Luis Potosí to San Diego. Monday has instead the fewest connections, with only 6 daily coaches between San Luis Potosí and San Diego.

The busiest time of the day is the Morning, with 23 buses from San Luis Potosí to San Diego, while Night sees the fewest connections between San Luis Potosí and San Diego, with 1 offers.

Facts about the bus from San Luis Potosí to San Diego

Compare all providers like Flix Mexico that travel 9 times every day by bus from San Luis Potosí to San Diego in one click! Book your bus ticket from San Luis Potosí to San Diego starting from $215!

Cheapest Bus	$215
Fastest Bus	53h 30m
Earliest Bus	5:00 AM
Latest Bus	10:05 PM
Daily Bus Routes	9 Ø
Distance	1,231.0 miles
Bus Companies	Flix Mexico

Cheapest bus connections from San Luis Potosí to San Diego

Every day, 9 buses from 1 bus companies leave San Luis Potosí for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/04/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

$216

Tuesday 05/05

$216

Wednesday 05/06

Thursday 05/07

Friday 05/08

$219

Saturday 05/09

$221

Sunday 05/10

$220

Monday 05/11

$219

Tuesday 05/12

$220

Wednesday 05/13

$220

Thursday 05/14

Friday 05/15

$220

Saturday 05/16

$220

Sunday 05/17

$220

Monday 05/18

$220

Tuesday 05/19

$221

Wednesday 05/20

$222

Thursday 05/21

$220

Friday 05/22

Saturday 05/23

$220

Sunday 05/24

$220

Monday 05/25

$220

Tuesday 05/26

$218

Wednesday 05/27

$220

Thursday 05/28

$220

Friday 05/29

$219

Saturday 05/30

The cheapest time to travel from San Luis Potosí to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Luis Potosí to San Diego, for the next 30 days.

With a price starting from $215, Friday is the cheapest day for a bus from San Luis Potosí to San Diego. Saturday instead is the most expensive day with prices starting from $220.

Morning is the cheapest day time for bus tickets from San Luis Potosí to San Diego, with $215. Afternoon is the most expensive time of the day with prices starting from $217.

How to save money travelling from San Luis Potosí to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Luis Potosí to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Luis Potosí to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Luis Potosí to San Diego are also emptier.

All bus stations and stops in San Luis Potosí and San Diego

In the map below, you can see where to find all bus stations in San Luis Potosí and San Diego.

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Bus Stop

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from San Luis Potosí to San Diego

Want to know which seat classes are available on the buses from San Luis Potosí to San Diego? Or which bus companies serve the route San Luis Potosí to San Diego? Below you will find answers to your questions.

FAQs about the San Luis Potosí to San Diego bus

How much does a San Luis Potosí San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $215 and takes 54h 0m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Luis Potosí to San Diego?

This route is offered by 1 companies with a range of ticket prices between $215 and $238. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Luis Potosí to San Diego each day?

Every day, the San Luis Potosí to San Diego bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Luis Potosí to San Diego take?

The fastest bus from San Luis Potosí to San Diego is offered by Flix Mexico and takes 53h 30m. Bus tickets for this connection cost $222. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Luis Potosí to San Diego?

The earliest bus arriving in San Diego from San Luis Potosí starts at 5:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Luis Potosí to San Diego?

The latest bus trip departing from San Luis Potosí for San Diego starts at 10:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Luis Potosí San Diego route?

When traveling by bus from San Luis Potosí to San Diego, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Luis Potosí and San Diego?

You can check all the direct connections between San Luis Potosí and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the San Luis Potosí to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Luis Potosí San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Luis Potosí San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Luis Potosí to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from San Luis Potosí to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between San Luis Potosí and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Luis Potosí to San Diego?

Prices and availability for 9 trips between San Luis Potosí and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Luis Potosí to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Luis Potosí and to San Diego

Here’s an overview of the most popular bus routes to San Luis Potosí and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!