Bus Knoxville, TN to Los Angeles - Compare all Companies

Compare all timetables for the bus from Knoxville, TN to Los Angeles

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Los Angeles from various bus operators like Greyhound US for the next days.

today

tomorrow

$225

Wednesday

$245

Thursday

Friday

$501

Saturday

Sunday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	49h 40m	6:10 PM	Knoxville, TN	Greyhound Bus Station	4:50 PM	Los Angeles	North Hollywood		Economy	$225	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/23/2025 6:10:00 PM to North Hollywood, Los Angeles (USA) arriving at 12/25/2025 4:50:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 49h 40m
	Greyhound US	56h 0m	7:05 PM	Knoxville, TN	Greyhound Bus Station	12:05 AM	Los Angeles	North Hollywood		Economy	$259	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/23/2025 7:05:00 PM to North Hollywood, Los Angeles (USA) arriving at 12/26/2025 12:05:00 AM. 50 Economy ticket for $259 per person are available. Travel duration is 56h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 25m	7:05 PM	Knoxville, TN	Greyhound Bus Station	10:30 PM	Los Angeles	Union Station	Economy	$245	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/24/2025 7:05:00 PM to Union Station, Los Angeles (USA) arriving at 12/26/2025 10:30:00 PM. 50 Economy ticket for $245 per person are available. Travel duration is 54h 25m
Greyhound US	47h 40m	6:10 PM	Knoxville, TN	Greyhound Bus Station	2:50 PM	Los Angeles	Union Station	Economy	$251	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/24/2025 6:10:00 PM to Union Station, Los Angeles (USA) arriving at 12/26/2025 2:50:00 PM. 50 Economy ticket for $251 per person are available. Travel duration is 47h 40m
Greyhound US	47h 50m	6:10 PM	Knoxville, TN	Greyhound Bus Station	3:00 PM	Los Angeles	Union Station	Economy	$251	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/24/2025 6:10:00 PM to Union Station, Los Angeles (USA) arriving at 12/26/2025 3:00:00 PM. 50 Economy ticket for $251 per person are available. Travel duration is 47h 50m
Greyhound US	70h 55m	7:05 PM	Knoxville, TN	Greyhound Bus Station	3:00 PM	Los Angeles	Union Station	Economy	$261	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/24/2025 7:05:00 PM to Union Station, Los Angeles (USA) arriving at 12/27/2025 3:00:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 70h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	47h 40m	6:10 PM	Knoxville, TN	Greyhound Bus Station	2:50 PM	Los Angeles	Union Station	Economy	$501	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/26/2025 6:10:00 PM to Union Station, Los Angeles (USA) arriving at 12/28/2025 2:50:00 PM. 50 Economy ticket for $501 per person are available. Travel duration is 47h 40m
Greyhound US	47h 50m	6:10 PM	Knoxville, TN	Greyhound Bus Station	3:00 PM	Los Angeles	Union Station	Economy	$501	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/26/2025 6:10:00 PM to Union Station, Los Angeles (USA) arriving at 12/28/2025 3:00:00 PM. 50 Economy ticket for $501 per person are available. Travel duration is 47h 50m
Greyhound US	70h 55m	7:05 PM	Knoxville, TN	Greyhound Bus Station	3:00 PM	Los Angeles	Union Station	Economy	$515	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/26/2025 7:05:00 PM to Union Station, Los Angeles (USA) arriving at 12/29/2025 3:00:00 PM. 50 Economy ticket for $515 per person are available. Travel duration is 70h 55m
Greyhound US	54h 25m	7:05 PM	Knoxville, TN	Greyhound Bus Station	10:30 PM	Los Angeles	Union Station	Economy	$553	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/26/2025 7:05:00 PM to Union Station, Los Angeles (USA) arriving at 12/28/2025 10:30:00 PM. 50 Economy ticket for $553 per person are available. Travel duration is 54h 25m

Did you know that if you travel from Huntington Park, CA to Knoxville, TN via Los Angeles, you can save more than $497? You will find the corresponding connections below.
- Save more than 99%
  
  0h 20m
  
  0 mi
  
  6:50 PM
  
  Huntington Park, CA
  East Florence Ave Bus Station
  
  7:10 PM
  
  Los Angeles
  University of Southern California (curbside)
  
  1937 mi
  
  Knoxville, TN
  
  Economy
  
  $4
  
  A Bus from goes from East Florence Ave Bus Station, Huntington Park, CA (USA) at 12/26/2025 6:50:00 PM to University of Southern California (curbside), Los Angeles (USA) arriving at 12/26/2025 7:10:00 PM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 20m
Did you know that if you travel from Knoxville, TN to Los Angeles via Nashville, you can save more than $248? You can find the corresponding connections below.
- FlixBus
  
  55h 20m
  
  0
  
  6:10 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  7:55 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $49
  
  A Bus from FlixBus goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/23/2025 6:10:00 PM to 5th Ave South Station, Nashville (USA) arriving at 12/23/2025 7:55:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 2h 45m
- Busbud
  
  44h 30m
  
  0
  
  4:00 AM
  
  Nashville
  5th Ave South Station
  
  10:30 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $204
  
  A Bus from Busbud goes from 5th Ave South Station, Nashville (USA) at 12/24/2025 4:00:00 AM to Union Station, Los Angeles (USA) arriving at 12/25/2025 10:30:00 PM. 50 Economy ticket for $204 per person are available. Travel duration is 44h 30m
Travel time is 10h 40m longer, but you will save $248

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Los Angeles is $209 on 12/30/2025. Flexible travelers save on ticket prices.

Facts about the bus from Knoxville, TN to Los Angeles

Compare all providers like Greyhound US that travel 3 times every day by bus from Knoxville, TN to Los Angeles in one click! Book your bus ticket from Knoxville, TN to Los Angeles starting from $209!

Cheapest Bus	$209
Fastest Bus	44h 40m
Earliest Bus	6:10 PM
Latest Bus	7:05 PM
Daily Bus Routes	3 Ø
Distance	1,937.3 miles
Bus Companies	Greyhound US

Cheapest bus connections from Knoxville, TN to Los Angeles

Every day, 3 buses from 1 bus companies leave Knoxville, TN for Los Angeles: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/22/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

Tuesday 12/23

$225

Wednesday 12/24

$245

Thursday 12/25

Friday 12/26

$501

Saturday 12/27

Sunday 12/28

Monday 12/29

$260

Tuesday 12/30

$209

Wednesday 12/31

$213

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

Sunday 01/11

Monday 01/12

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

Friday 01/16

Saturday 01/17

How to save money travelling from Knoxville, TN to Los Angeles

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Los Angeles in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Los Angeles, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Los Angeles are also emptier.

Beloved bus companies from Knoxville, TN to Los Angeles

These are the most booked bus companies between Knoxville, TN to Los Angeles from our users.

Greyhound US from Knoxville, TN to Los Angeles

Here you will find the key facts about the Greyhound US bus route Knoxville, TN to Los Angeles:

Cheapest Price	$225
Fastest Bus	44h 40m
Earliest Bus	6:10 PM
Last Bus	7:05 PM
Daily Connections	3 Ø
Found on	12/18/2025

All bus stations and stops in Knoxville, TN and Los Angeles

In the map below, you can see where to find all bus stations in Knoxville, TN and Los Angeles.

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Downtown Bus Station

N Main St 512

Las Casas

Main Street 94

Tufesa

Maple Ave 611

Union Station

Ramirez Street 401-479

Amtrak

Alameda Street 738-788

Service and Comfort on the bus from Knoxville, TN to Los Angeles

Want to know which seat classes are available on the buses from Knoxville, TN to Los Angeles? Or which bus companies serve the route Knoxville, TN to Los Angeles? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Los Angeles bus

How much does a Knoxville, TN Los Angeles bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $209 and takes 46h 40m to reach Los Angeles. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Los Angeles?

This route is offered by 1 companies with a range of ticket prices between $209 and $553. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Los Angeles.

On average, how many connections are available from Knoxville, TN to Los Angeles each day?

Every day, the Knoxville, TN to Los Angeles bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Los Angeles take?

The fastest bus from Knoxville, TN to Los Angeles is offered by Greyhound US and takes 44h 40m. Bus tickets for this connection cost $251. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Los Angeles?

The earliest bus arriving in Los Angeles from Knoxville, TN starts at 6:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Los Angeles?

The latest bus trip departing from Knoxville, TN for Los Angeles starts at 7:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Los Angeles route?

When traveling by bus from Knoxville, TN to Los Angeles, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Los Angeles?

You can check all the direct connections between Knoxville, TN and Los Angeles by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Los Angeles bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Los Angeles bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Los Angeles bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Los Angeles on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Los Angeles?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Knoxville, TN and Los Angeles. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Los Angeles?

Prices and availability for 3 trips between Knoxville, TN and Los Angeles change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Los Angeles

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Los Angeles

Here’s an overview of the most popular bus routes to Knoxville, TN and to Los Angeles. Simply click on the connection of your choice, and you will find all the details about your bus route!