Bus Biloxi, MS to Knoxville, TN - Compare all Companies

Compare all timetables for the bus from Biloxi, MS to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Biloxi, MS to Knoxville, TN from various bus operators like Greyhound US for the next days.

today

tomorrow

$138

Wednesday

Thursday

$116

Friday

Saturday

Sunday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	29h 45m	3:05 PM	Biloxi, MS	Transit Center	9:50 PM	Knoxville, TN	Greyhound Bus Station		Economy	$138	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/20/2026 3:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 1/21/2026 9:50:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 29h 45m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	35h 45m	9:55 AM	Biloxi, MS	Transit Center	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop		Economy	$116	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/22/2026 9:55:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 1/23/2026 10:40:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 35h 45m

Best Price Offer: The price for the cheapest bus from Biloxi, MS to Knoxville, TN is $116 on 1/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Biloxi, MS and Knoxville, TN

See here how frequent the connections between Biloxi, MS and Knoxville, TN are, during different times and days of the week.

Tuesday is the busiest day, with more than 1 daily buses from Biloxi, MS to Knoxville, TN. Tuesday has instead the fewest connections, with only 1 daily coaches between Biloxi, MS and Knoxville, TN.

The busiest time of the day is the Morning, with 1 buses from Biloxi, MS to Knoxville, TN, while Morning sees the fewest connections between Biloxi, MS and Knoxville, TN, with 1 offers.

Facts about the bus from Biloxi, MS to Knoxville, TN

Compare all providers like Greyhound US that travel 1 times every day by bus from Biloxi, MS to Knoxville, TN in one click! Book your bus ticket from Biloxi, MS to Knoxville, TN starting from $116!

Cheapest Bus	$116
Fastest Bus	30h 45m
Earliest Bus	3:05 PM
Latest Bus	9:55 AM
Daily Bus Routes	1 Ø
Distance	480.3 miles
Bus Companies	Greyhound US

Cheapest bus connections from Biloxi, MS to Knoxville, TN

Every day, 1 buses from 1 bus companies leave Biloxi, MS for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

Tuesday 01/20

$138

Wednesday 01/21

Thursday 01/22

$116

Friday 01/23

Saturday 01/24

Sunday 01/25

Monday 01/26

$136

Tuesday 01/27

$133

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Biloxi, MS to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Biloxi, MS to Knoxville, TN, for the next 30 days.

With a price starting from $115, Thursday is the cheapest day for a bus from Biloxi, MS to Knoxville, TN. Tuesday instead is the most expensive day with prices starting from $133.

Morning is the cheapest day time for bus tickets from Biloxi, MS to Knoxville, TN, with $115. Afternoon is the most expensive time of the day with prices starting from $137.

How to save money travelling from Biloxi, MS to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Biloxi, MS to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Biloxi, MS to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Biloxi, MS to Knoxville, TN are also emptier.

All bus stations and stops in Biloxi, MS and Knoxville, TN

In the map below, you can see where to find all bus stations in Biloxi, MS and Knoxville, TN.

Transit Center

Dr Martin Luther King Jr Blvd 820

Love's Travel Stop

Cedar Lake Rd 11347

Point Cadet

Myrtle St

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Service and Comfort on the bus from Biloxi, MS to Knoxville, TN

Want to know which seat classes are available on the buses from Biloxi, MS to Knoxville, TN? Or which bus companies serve the route Biloxi, MS to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Biloxi, MS to Knoxville, TN bus

How much does a Biloxi, MS Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $116 and takes 36h 45m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Biloxi, MS to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $116 and $138. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Biloxi, MS to Knoxville, TN each day?

Every day, the Biloxi, MS to Knoxville, TN bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Biloxi, MS to Knoxville, TN take?

The fastest bus from Biloxi, MS to Knoxville, TN is offered by Greyhound US and takes 30h 45m. Bus tickets for this connection cost $138. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Biloxi, MS to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Biloxi, MS starts at 3:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Biloxi, MS to Knoxville, TN?

The latest bus trip departing from Biloxi, MS for Knoxville, TN starts at 9:55 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Biloxi, MS Knoxville, TN route?

When traveling by bus from Biloxi, MS to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Biloxi, MS and Knoxville, TN?

You can check all the direct connections between Biloxi, MS and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Biloxi, MS to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Biloxi, MS Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Biloxi, MS Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Biloxi, MS to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Biloxi, MS to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Biloxi, MS and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Biloxi, MS to Knoxville, TN?

Prices and availability for 1 trips between Biloxi, MS and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Biloxi, MS to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Biloxi, MS and to Knoxville, TN

Here’s an overview of the most popular bus routes to Biloxi, MS and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!