Bus Greenville, SC to Orlando, FL - Compare all Companies

Compare all timetables for the bus from Greenville, SC to Orlando, FL

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Orlando, FL from various bus operators like Greyhound US or FlixBus for the next days.

today

$69

tomorrow

$78

Wednesday

$76

Thursday

$94

Friday

$84

Saturday

Sunday

$76

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 5m	7:10 AM	Greenville, SC	Woodruff Rd	9:15 PM	Orlando, FL	Bus Station	Economy	$69	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/22/2026 7:10:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/22/2026 9:15:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 5m
Greyhound US	12h 5m	11:15 AM	Greenville, SC	Woodruff Rd	11:20 PM	Orlando, FL	Bus Station	Economy	$70	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/22/2026 11:15:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/22/2026 11:20:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 12h 5m
Greyhound US	12h 5m	5:45 PM	Greenville, SC	Woodruff Rd	5:50 AM	Orlando, FL	Bus Station	Economy	$70	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/22/2026 5:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/23/2026 5:50:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 12h 5m
FlixBus	12h 30m	1:20 PM	Greenville, SC	Woodruff Rd	1:50 AM	Orlando, FL	Bus Station	Economy	$72	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/22/2026 1:20:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/23/2026 1:50:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 12h 30m
FlixBus	18h 45m	9:35 PM	Greenville, SC	Woodruff Rd	4:20 PM	Orlando, FL	Bus Station	Economy	$73	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/22/2026 9:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/23/2026 4:20:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 5m	7:10 AM	Greenville, SC	Woodruff Rd	9:15 PM	Orlando, FL	Bus Station	Economy	$78	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/23/2026 7:10:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/23/2026 9:15:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 14h 5m
Greyhound US	12h 5m	11:15 AM	Greenville, SC	Woodruff Rd	11:20 PM	Orlando, FL	Bus Station	Economy	$78	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/23/2026 11:15:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/23/2026 11:20:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 5m
Greyhound US	15h 5m	2:45 PM	Greenville, SC	Woodruff Rd	5:50 AM	Orlando, FL	Bus Station	Economy	$78	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/23/2026 2:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/24/2026 5:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 5m
FlixBus	12h 30m	1:20 PM	Greenville, SC	Woodruff Rd	1:50 AM	Orlando, FL	Bus Station	Economy	$78	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/23/2026 1:20:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/24/2026 1:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 30m
FlixBus	18h 45m	9:35 PM	Greenville, SC	Woodruff Rd	4:20 PM	Orlando, FL	Bus Station	Economy	$81	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/23/2026 9:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/24/2026 4:20:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 18h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 5m	7:10 AM	Greenville, SC	Woodruff Rd	9:15 PM	Orlando, FL	Bus Station	Economy	$76	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/24/2026 7:10:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/24/2026 9:15:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 14h 5m
Greyhound US	12h 44m	11:15 AM	Greenville, SC	Woodruff Rd	11:59 PM	Orlando, FL	Florida Mall	Economy	$76	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/24/2026 11:15:00 AM to Florida Mall, Orlando, FL (USA) arriving at 6/24/2026 11:59:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 44m
Greyhound US	12h 5m	11:15 AM	Greenville, SC	Woodruff Rd	11:20 PM	Orlando, FL	Bus Station	Economy	$77	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/24/2026 11:15:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/24/2026 11:20:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 5m
FlixBus	18h 45m	9:35 PM	Greenville, SC	Woodruff Rd	4:20 PM	Orlando, FL	Bus Station	Economy	$79	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/24/2026 9:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/25/2026 4:20:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	18h 35m	8:20 PM	Greenville, SC	Woodruff Rd	2:55 PM	Orlando, FL	Florida Mall	Economy	$94	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/25/2026 8:20:00 PM to Florida Mall, Orlando, FL (USA) arriving at 6/26/2026 2:55:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 18h 35m
Greyhound US	12h 44m	11:15 AM	Greenville, SC	Woodruff Rd	11:59 PM	Orlando, FL	Florida Mall	Economy	$100	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/25/2026 11:15:00 AM to Florida Mall, Orlando, FL (USA) arriving at 6/25/2026 11:59:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 12h 44m
FlixBus	18h 45m	9:35 PM	Greenville, SC	Woodruff Rd	4:20 PM	Orlando, FL	Bus Station	Economy	$101	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/25/2026 9:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/26/2026 4:20:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 18h 45m
Greyhound US	14h 5m	7:10 AM	Greenville, SC	Woodruff Rd	9:15 PM	Orlando, FL	Bus Station	Economy	$102	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/25/2026 7:10:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/25/2026 9:15:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 14h 5m
FlixBus	12h 30m	1:20 PM	Greenville, SC	Woodruff Rd	1:50 AM	Orlando, FL	Bus Station	Economy	$116	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/25/2026 1:20:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/26/2026 1:50:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 12h 30m

Did you know that if you travel from Greenville, SC to Orlando, FL via Gainesville, FL, you can save more than $9? You can find the corresponding connections below.
- Greyhound US
  
  11h 30m
  
  0
  
  8:20 PM
  
  Greenville, SC
  Woodruff Rd
  
  5:15 AM
  
  Gainesville, FL
  Rosa Parks Transfer station
  
  0
  
  Economy
  
  $61
  
  A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/23/2026 8:20:00 PM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 6/24/2026 5:15:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 8h 55m
- FlixBus
  
  2h 30m
  
  0
  
  5:20 AM
  
  Gainesville, FL
  Rosa Parks Transfer station
  
  7:50 AM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $23
  
  A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 6/24/2026 5:20:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/24/2026 7:50:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 30m
Travel Time is 1h 0m shorter, and you will save $9

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 5m	7:10 AM	Greenville, SC	Woodruff Rd	9:15 PM	Orlando, FL	Bus Station	Economy	$84	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/26/2026 7:10:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/26/2026 9:15:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 5m
Greyhound US	12h 5m	11:15 AM	Greenville, SC	Woodruff Rd	11:20 PM	Orlando, FL	Bus Station	Economy	$84	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/26/2026 11:15:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/26/2026 11:20:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 12h 5m
Greyhound US	15h 5m	2:45 PM	Greenville, SC	Woodruff Rd	5:50 AM	Orlando, FL	Bus Station	Economy	$84	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/26/2026 2:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/27/2026 5:50:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 15h 5m
FlixBus	12h 30m	1:20 PM	Greenville, SC	Woodruff Rd	1:50 AM	Orlando, FL	Bus Station	Economy	$84	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/26/2026 1:20:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/27/2026 1:50:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 12h 30m
FlixBus	18h 45m	9:35 PM	Greenville, SC	Woodruff Rd	4:20 PM	Orlando, FL	Bus Station	Economy	$85	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/26/2026 9:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/27/2026 4:20:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 18h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 44m	11:15 AM	Greenville, SC	Woodruff Rd	11:59 PM	Orlando, FL	Florida Mall	Economy	$76	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/28/2026 11:15:00 AM to Florida Mall, Orlando, FL (USA) arriving at 6/28/2026 11:59:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 44m
Greyhound US	12h 5m	11:15 AM	Greenville, SC	Woodruff Rd	11:20 PM	Orlando, FL	Bus Station	Economy	$77	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/28/2026 11:15:00 AM to Bus Station, Orlando, FL (USA) arriving at 6/28/2026 11:20:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 5m
Greyhound US	15h 5m	2:45 PM	Greenville, SC	Woodruff Rd	5:50 AM	Orlando, FL	Bus Station	Economy	$77	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/28/2026 2:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/29/2026 5:50:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 5m
FlixBus	12h 30m	1:20 PM	Greenville, SC	Woodruff Rd	1:50 AM	Orlando, FL	Bus Station	Economy	$78	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/28/2026 1:20:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/29/2026 1:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 30m
FlixBus	18h 45m	9:35 PM	Greenville, SC	Woodruff Rd	4:20 PM	Orlando, FL	Bus Station	Economy	$78	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/28/2026 9:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 6/29/2026 4:20:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 18h 45m

Best Price Offer: The price for the cheapest bus from Greenville, SC to Orlando, FL is $69 on 6/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Greenville, SC and Orlando, FL

See here how frequent the connections between Greenville, SC and Orlando, FL are, during different times and days of the week.

Thursday is the busiest day, with more than 20 daily buses from Greenville, SC to Orlando, FL. Tuesday has instead the fewest connections, with only 7 daily coaches between Greenville, SC and Orlando, FL.

The busiest time of the day is the Morning, with 35 buses from Greenville, SC to Orlando, FL, while Afternoon sees the fewest connections between Greenville, SC and Orlando, FL, with 21 offers.

Facts about the bus from Greenville, SC to Orlando, FL

Compare all providers like Greyhound US and FlixBus that travel 14 times every day by bus from Greenville, SC to Orlando, FL in one click! Book your bus ticket from Greenville, SC to Orlando, FL starting from $69!

Cheapest Bus	$69
Fastest Bus	11h 30m
Earliest Bus	7:10 AM
Latest Bus	9:35 PM
Daily Bus Routes	14 Ø
Distance	440.3 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Greenville, SC to Orlando, FL

Every day, 14 buses from 2 bus companies leave Greenville, SC for Orlando, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

$69

Tuesday 06/23

$78

Wednesday 06/24

$76

Thursday 06/25

$94

Friday 06/26

$84

Saturday 06/27

Sunday 06/28

$80

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

$110

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

$95

Friday 07/10

$100

Saturday 07/11

$77

Sunday 07/12

$85

Monday 07/13

$79

Tuesday 07/14

$80

Wednesday 07/15

$81

Thursday 07/16

$76

Friday 07/17

$83

Saturday 07/18

The cheapest time to travel from Greenville, SC to Orlando, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Orlando, FL, for the next 30 days.

With a price starting from $69, Monday is the cheapest day for a bus from Greenville, SC to Orlando, FL. Friday instead is the most expensive day with prices starting from $83.

Morning is the cheapest day time for bus tickets from Greenville, SC to Orlando, FL, with $69. Evening is the most expensive time of the day with prices starting from $71.

How to save money travelling from Greenville, SC to Orlando, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Orlando, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Orlando, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Orlando, FL are also emptier.

All bus stations and stops in Greenville, SC and Orlando, FL

In the map below, you can see where to find all bus stations in Greenville, SC and Orlando, FL.

Woodruff Rd

Woodruff Rd 1116

N Church St

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

McDonald's

Woodruff Rd 1111

Bus Station

N John Young Pkwy 555

Florida Mall

Florida Mall Avenue 1602

RedCoach Station

Belle Isle

Universal Studio Orlando Resort

Universal Blvd 5800

Seaworld Hotels

International Dr 10100

Service and Comfort on the bus from Greenville, SC to Orlando, FL

Want to know which seat classes are available on the buses from Greenville, SC to Orlando, FL? Or which bus companies serve the route Greenville, SC to Orlando, FL? Below you will find answers to your questions.

FAQs about the Greenville, SC to Orlando, FL bus

How much does a Greenville, SC Orlando, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $69 and takes 14h 5m to reach Orlando, FL. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Orlando, FL?

This route is offered by 2 companies with a range of ticket prices between $69 and $145. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Orlando, FL.

On average, how many connections are available from Greenville, SC to Orlando, FL each day?

Every day, the Greenville, SC to Orlando, FL bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Orlando, FL take?

The fastest bus from Greenville, SC to Orlando, FL is offered by Greyhound US and takes 11h 30m. Bus tickets for this connection cost $92. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Orlando, FL?

The earliest bus arriving in Orlando, FL from Greenville, SC starts at 7:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Orlando, FL?

The latest bus trip departing from Greenville, SC for Orlando, FL starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Orlando, FL route?

When traveling by bus from Greenville, SC to Orlando, FL, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Orlando, FL?

You can check all the direct connections between Greenville, SC and Orlando, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Greenville, SC to Orlando, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Orlando, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Orlando, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Orlando, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Orlando, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Greenville, SC and Orlando, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Orlando, FL?

Prices and availability for 14 trips between Greenville, SC and Orlando, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Orlando, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Orlando, FL

Here’s an overview of the most popular bus routes to Greenville, SC and to Orlando, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!