Bus St. Louis, MO to Houston: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Houston

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Houston from various bus operators like Greyhound US or FlixBus for the next days.

today

$110

tomorrow

Saturday

$145

Sunday

Monday

$134

Tuesday

Wednesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 10m	1:20 AM	St. Louis, MO	Gateway Station	10:30 PM	Houston	Harrisburg Blvd Station	Economy	$110	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/4/2025 1:20:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/4/2025 10:30:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 21h 10m
Greyhound US	25h 30m	4:30 PM	St. Louis, MO	Gateway Station	6:00 PM	Houston	Harrisburg Blvd Station	Economy	$110	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/4/2025 4:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/5/2025 6:00:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 25h 30m
FlixBus	20h 0m	4:00 PM	St. Louis, MO	Gateway Station	12:00 PM	Houston	Downtown Houston	Economy	$110	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/4/2025 4:00:00 PM to Downtown Houston, Houston (USA) arriving at 12/5/2025 12:00:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 20h 0m
FlixBus	20h 35m	4:00 PM	St. Louis, MO	Gateway Station	12:35 PM	Houston	Harrisburg Blvd Station	Economy	$110	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/4/2025 4:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/5/2025 12:35:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 20h 35m
Greyhound US	28h 15m	1:00 AM	St. Louis, MO	Gateway Station	5:15 AM	Houston	Downtown Houston	Economy	$111	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/4/2025 1:00:00 AM to Downtown Houston, Houston (USA) arriving at 12/5/2025 5:15:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 28h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 15m	1:00 AM	St. Louis, MO	Gateway Station	5:15 AM	Houston	Downtown Houston	Economy	$145	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 1:00:00 AM to Downtown Houston, Houston (USA) arriving at 12/7/2025 5:15:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 28h 15m
Greyhound US	21h 45m	1:30 AM	St. Louis, MO	Gateway Station	11:15 PM	Houston	Harrisburg Blvd Station	Economy	$145	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 1:30:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/6/2025 11:15:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 21h 45m
FlixBus	20h 0m	4:00 PM	St. Louis, MO	Gateway Station	12:00 PM	Houston	Downtown Houston	Economy	$145	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 4:00:00 PM to Downtown Houston, Houston (USA) arriving at 12/7/2025 12:00:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 20h 0m
Greyhound US	23h 50m	4:30 PM	St. Louis, MO	Gateway Station	4:20 PM	Houston	Downtown Houston	Economy	$146	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 4:30:00 PM to Downtown Houston, Houston (USA) arriving at 12/7/2025 4:20:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 23h 50m
FlixBus	20h 35m	4:00 PM	St. Louis, MO	Gateway Station	12:35 PM	Houston	Harrisburg Blvd Station	Economy	$146	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 4:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/7/2025 12:35:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 20h 35m

Did you know that if you travel from St. Louis, MO to Houston via Memphis, you can save more than $19? You can find the corresponding connections below.
- FlixBus
  
  22h 15m
  
  0
  
  1:00 AM
  
  St. Louis, MO
  Gateway Station
  
  6:30 AM
  
  Memphis
  Airways Transit Center
  
  0
  
  Economy
  
  $43
  
  A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:00:00 AM to Airways Transit Center, Memphis (USA) arriving at 12/8/2025 6:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 30m
- Busbud
  
  14h 10m
  
  0
  
  9:05 AM
  
  Memphis
  Airways Transit Center
  
  11:15 PM
  
  Houston
  Harrisburg Blvd Station
  
  0
  
  Economy
  
  $83
  
  A Bus from Busbud goes from Airways Transit Center, Memphis (USA) at 12/8/2025 9:05:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/8/2025 11:15:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 14h 10m
Travel time is 2h 15m longer, but you will save $19

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 15m	1:00 AM	St. Louis, MO	Gateway Station	5:15 AM	Houston	Downtown Houston	Economy	$134	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:00:00 AM to Downtown Houston, Houston (USA) arriving at 12/9/2025 5:15:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 28h 15m
Greyhound US	23h 50m	4:30 PM	St. Louis, MO	Gateway Station	4:20 PM	Houston	Downtown Houston	Economy	$135	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 4:30:00 PM to Downtown Houston, Houston (USA) arriving at 12/9/2025 4:20:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 23h 50m
Greyhound US	21h 10m	1:20 AM	St. Louis, MO	Gateway Station	10:30 PM	Houston	Harrisburg Blvd Station	Economy	$135	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 1:20:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/8/2025 10:30:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 21h 10m
FlixBus	20h 0m	4:00 PM	St. Louis, MO	Gateway Station	12:00 PM	Houston	Downtown Houston	Economy	$135	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 4:00:00 PM to Downtown Houston, Houston (USA) arriving at 12/9/2025 12:00:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 0m
FlixBus	20h 40m	4:00 PM	St. Louis, MO	Gateway Station	12:40 PM	Houston	Harrisburg Blvd Station	Economy	$135	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 4:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/9/2025 12:40:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 40m

Did you know that if you travel from St. Louis, MO to Houston via Memphis, you can save more than $30? You can find the corresponding connections below.
- FlixBus
  
  20h 0m
  
  0
  
  4:00 PM
  
  St. Louis, MO
  Gateway Station
  
  8:45 PM
  
  Memphis
  Airways Transit Center
  
  0
  
  Economy
  
  $43
  
  A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/8/2025 4:00:00 PM to Airways Transit Center, Memphis (USA) arriving at 12/8/2025 8:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 4h 45m
- Busbud
  
  13h 45m
  
  0
  
  10:15 PM
  
  Memphis
  Airways Transit Center
  
  12:00 PM
  
  Houston
  Downtown Houston
  
  0
  
  Economy
  
  $61
  
  A Bus from Busbud goes from Airways Transit Center, Memphis (USA) at 12/8/2025 10:15:00 PM to Downtown Houston, Houston (USA) arriving at 12/9/2025 12:00:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 45m
Travel time is the same as the direct connection, but you will save $30

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Houston is $110 on 12/4/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Houston

See here how frequent the connections between St. Louis, MO and Houston are, during different times and days of the week.

Monday is the busiest day, with more than 20 daily buses from St. Louis, MO to Houston. Saturday has instead the fewest connections, with only 10 daily coaches between St. Louis, MO and Houston.

The busiest time of the day is the Afternoon, with 35 buses from St. Louis, MO to Houston, while Night sees the fewest connections between St. Louis, MO and Houston, with 15 offers.

Facts about the bus from St. Louis, MO to Houston

Compare all providers like Greyhound US and FlixBus that travel 16 times every day by bus from St. Louis, MO to Houston in one click! Book your bus ticket from St. Louis, MO to Houston starting from $110!

Cheapest Bus	$110
Fastest Bus	20h 0m
Earliest Bus	1:00 AM
Latest Bus	4:30 PM
Daily Bus Routes	16 Ø
Distance	680.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Houston

Every day, 16 buses from 2 bus companies leave St. Louis, MO for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

$110

Friday 12/05

Saturday 12/06

$145

Sunday 12/07

Monday 12/08

$134

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

$121

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$131

Thursday 12/18

$130

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

$153

Tuesday 12/23

$147

Wednesday 12/24

Thursday 12/25

$141

Friday 12/26

Saturday 12/27

The cheapest time to travel from St. Louis, MO to Houston

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Houston, for the next 30 days.

With a price starting from $110, Thursday is the cheapest day for a bus from St. Louis, MO to Houston. Saturday instead is the most expensive day with prices starting from $145.

Afternoon is the cheapest day time for bus tickets from St. Louis, MO to Houston, with $110. Afternoon is the most expensive time of the day with prices starting from $110.

How to save money travelling from St. Louis, MO to Houston

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Houston, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Houston are also emptier.

Beloved bus companies from St. Louis, MO to Houston

These are the most booked bus companies between St. Louis, MO to Houston from our users.

Greyhound US from St. Louis, MO to Houston

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to Houston:

Cheapest Price	$110
Fastest Bus	21h 10m
Earliest Bus	1:00 AM
Last Bus	4:30 PM
Daily Connections	10 Ø
Found on	11/30/2025

FlixBus from St. Louis, MO to Houston

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Houston:

Cheapest Price	$110
Fastest Bus	20h 0m
Earliest Bus	4:00 PM
Last Bus	4:00 PM
Daily Connections	6 Ø
Found on	11/30/2025

All bus stations and stops in St. Louis, MO and Houston

In the map below, you can see where to find all bus stations in St. Louis, MO and Houston.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Uptown/Upper Kirby

Southwest Fwy 2525

Chase Bank

Milam Street 212

Service and Comfort on the bus from St. Louis, MO to Houston

Want to know which seat classes are available on the buses from St. Louis, MO to Houston? Or which bus companies serve the route St. Louis, MO to Houston? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Houston bus

How much does a St. Louis, MO Houston bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 21h 10m to reach Houston. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Houston?

This route is offered by 2 companies with a range of ticket prices between $110 and $152. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Houston.

On average, how many connections are available from St. Louis, MO to Houston each day?

Every day, the St. Louis, MO to Houston bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Houston take?

The fastest bus from St. Louis, MO to Houston is offered by FlixBus and takes 20h 0m. Bus tickets for this connection cost $135. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Houston?

The earliest bus arriving in Houston from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Houston?

The latest bus trip departing from St. Louis, MO for Houston starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Houston route?

When traveling by bus from St. Louis, MO to Houston, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Houston?

You can check all the direct connections between St. Louis, MO and Houston by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Houston bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Houston bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Houston bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Houston on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to Houston

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Houston

Here’s an overview of the most popular bus routes to St. Louis, MO and to Houston. Simply click on the connection of your choice, and you will find all the details about your bus route!