Compare all timetables for the bus from St. Louis, MO to Houston
Cheapest bus trips today
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Greyhound US20h 55m01:35 AMSt. Louis, MOGateway Station10:30 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/21/2025 1:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 5/21/2025 10:30:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 55m
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Greyhound US26h 30m04:30 PMSt. Louis, MOGateway Station7:00 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/21/2025 4:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/22/2025 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 26h 30m
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FlixBus20h 20m04:15 PMSt. Louis, MOGateway Station12:35 PMHoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/21/2025 4:15:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/22/2025 12:35:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 20h 20m
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FlixBus30h 25m04:15 PMSt. Louis, MOGateway Station10:40 PMHoustonSW Agencia Autobuses0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/21/2025 4:15:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 5/22/2025 10:40:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 30h 25m
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FlixBus21h 55m04:15 PMSt. Louis, MOGateway Station2:10 PMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/21/2025 4:15:00 PM to Downtown Houston, Houston (USA) arriving at 5/22/2025 2:10:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 21h 55m
Cheapest bus trips tomorrow
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FlixBus20h 20m04:15 PMSt. Louis, MOGateway Station12:35 PMHoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/22/2025 4:15:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/23/2025 12:35:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 20h 20m
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FlixBus30h 25m04:15 PMSt. Louis, MOGateway Station10:40 PMHoustonSW Agencia Autobuses0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/22/2025 4:15:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 5/23/2025 10:40:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 30h 25m
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FlixBus19h 45m04:15 PMSt. Louis, MOGateway Station12:00 PMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/22/2025 4:15:00 PM to Downtown Houston, Houston (USA) arriving at 5/23/2025 12:00:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 19h 45m
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Greyhound US26h 30m04:30 PMSt. Louis, MOGateway Station7:00 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/22/2025 4:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/23/2025 7:00:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 26h 30m
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Greyhound US23h 50m04:30 PMSt. Louis, MOGateway Station4:20 PMHoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/22/2025 4:30:00 PM to Downtown Houston, Houston (USA) arriving at 5/23/2025 4:20:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 23h 50m
Cheapest bus trips Friday
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Greyhound US23h 50m04:30 PMSt. Louis, MOGateway Station4:20 PMHoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/23/2025 4:30:00 PM to Downtown Houston, Houston (USA) arriving at 5/24/2025 4:20:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 23h 50m
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Greyhound US24h 20m04:30 PMSt. Louis, MOGateway Station4:50 PMHoustonUptown/Upper Kirby0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/23/2025 4:30:00 PM to Uptown/Upper Kirby, Houston (USA) arriving at 5/24/2025 4:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 24h 20m
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FlixBus28h 0m08:00 AMSt. Louis, MOGateway Station12:00 PMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/23/2025 8:00:00 AM to Downtown Houston, Houston (USA) arriving at 5/24/2025 12:00:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 28h 0m
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FlixBus27h 45m08:00 AMSt. Louis, MOGateway Station11:45 AMHoustonMain St & Airline Dr0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/23/2025 8:00:00 AM to Main St & Airline Dr, Houston (USA) arriving at 5/24/2025 11:45:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 27h 45m
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FlixBus30h 25m04:15 PMSt. Louis, MOGateway Station10:40 PMHoustonSW Agencia Autobuses0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/23/2025 4:15:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 5/24/2025 10:40:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 30h 25m
Cheapest bus trips Saturday
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FlixBus34h 20m07:00 PMSt. Louis, MOGateway Station5:20 AMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 7:00:00 PM to Downtown Houston, Houston (USA) arriving at 5/26/2025 5:20:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 34h 20m
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Greyhound US23h 50m04:30 PMSt. Louis, MOGateway Station4:20 PMHoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 4:30:00 PM to Downtown Houston, Houston (USA) arriving at 5/25/2025 4:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 23h 50m
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Greyhound US24h 20m04:30 PMSt. Louis, MOGateway Station4:50 PMHoustonUptown/Upper Kirby0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 4:30:00 PM to Uptown/Upper Kirby, Houston (USA) arriving at 5/25/2025 4:50:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 24h 20m
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FlixBus19h 45m04:15 PMSt. Louis, MOGateway Station12:00 PMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 4:15:00 PM to Downtown Houston, Houston (USA) arriving at 5/25/2025 12:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 19h 45m
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FlixBus34h 20m07:00 PMSt. Louis, MOGateway Station5:20 AMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 7:00:00 PM to Downtown Houston, Houston (USA) arriving at 5/26/2025 5:20:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 34h 20m
Cheapest bus trips Sunday
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Greyhound US28h 15m01:05 AMSt. Louis, MOGateway Station5:20 AMHoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 1:05:00 AM to Downtown Houston, Houston (USA) arriving at 5/26/2025 5:20:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 28h 15m
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Greyhound US20h 55m01:35 AMSt. Louis, MOGateway Station10:30 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 1:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 5/25/2025 10:30:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 20h 55m
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Greyhound US26h 30m04:30 PMSt. Louis, MOGateway Station7:00 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 4:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/26/2025 7:00:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 26h 30m
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FlixBus30h 25m04:15 PMSt. Louis, MOGateway Station10:40 PMHoustonSW Agencia Autobuses0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 4:15:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 5/26/2025 10:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 30h 25m
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FlixBus22h 30m04:15 PMSt. Louis, MOGateway Station2:45 PMHoustonUptown/Upper Kirby0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 4:15:00 PM to Uptown/Upper Kirby, Houston (USA) arriving at 5/26/2025 2:45:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 22h 30m
Cheapest bus trips Monday
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FlixBus19h 45m04:15 PMSt. Louis, MOGateway Station12:00 PMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 4:15:00 PM to Downtown Houston, Houston (USA) arriving at 5/27/2025 12:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 19h 45m
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Greyhound US20h 55m01:35 AMSt. Louis, MOGateway Station10:30 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 1:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 5/26/2025 10:30:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 55m
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FlixBus34h 20m07:00 PMSt. Louis, MOGateway Station5:20 AMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 7:00:00 PM to Downtown Houston, Houston (USA) arriving at 5/28/2025 5:20:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 34h 20m
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Greyhound US26h 30m04:30 PMSt. Louis, MOGateway Station7:00 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 4:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/27/2025 7:00:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 30m
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Greyhound US23h 50m04:30 PMSt. Louis, MOGateway Station4:20 PMHoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 4:30:00 PM to Downtown Houston, Houston (USA) arriving at 5/27/2025 4:20:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 23h 50m
Cheapest bus trips Tuesday
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FlixBus19h 45m04:15 PMSt. Louis, MOGateway Station12:00 PMHoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/27/2025 4:15:00 PM to Downtown Houston, Houston (USA) arriving at 5/28/2025 12:00:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 19h 45m
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FlixBus20h 20m04:15 PMSt. Louis, MOGateway Station12:35 PMHoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/27/2025 4:15:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/28/2025 12:35:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 20h 20m
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FlixBus35h 30m04:15 PMSt. Louis, MOGateway Station3:45 AMHoustonSW Agencia Autobuses0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/27/2025 4:15:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 5/29/2025 3:45:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 35h 30m
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Greyhound US20h 55m01:35 AMSt. Louis, MOGateway Station10:30 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/27/2025 1:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 5/27/2025 10:30:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 20h 55m
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Greyhound US26h 30m04:30 PMSt. Louis, MOGateway Station7:00 PMHoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/27/2025 4:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 5/28/2025 7:00:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 26h 30m
Frequency of bus connections between St. Louis, MO and Houston
Facts about the bus from St. Louis, MO to Houston
Compare all providers like FlixBus and Greyhound US that travel 12 times every day by bus from St. Louis, MO to Houston in one click! Book your bus ticket from St. Louis, MO to Houston starting from $95!
Cheapest Bus | $95 |
Fastest Bus | 19h 30m |
Earliest Bus | 1:35 AM |
Latest Bus | 4:30 PM |
Daily Bus Routes | 12 Ø |
Distance | 680.5 miles |
Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from St. Louis, MO to Houston
Every day, 12 buses from 2 bus companies leave St. Louis, MO for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/21/2025 and for the following days.
The cheapest time to travel from St. Louis, MO to Houston
How to save money travelling from St. Louis, MO to Houston
Book the ticket from St. Louis, MO to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Houston, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Houston are also emptier.All bus stations and stops in St. Louis, MO and Houston
In the map below, you can see where to find all bus stations in St. Louis, MO and Houston.
Service and Comfort on the bus from St. Louis, MO to Houston
FAQs about the St. Louis, MO to Houston bus
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Available seat classes which are offered on the bus route St. Louis, MO to Houston
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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