Bus Knoxville, TN to San Antonio, TX

Compare all timetables for the bus from Knoxville, TN to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to San Antonio, TX from various bus operators like Greyhound US for the next days.

today

$107

tomorrow

Monday

$107

Tuesday

Wednesday

Thursday

$109

Friday

$114

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 15m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	6:10 PM	San Antonio, TX	Bus Station		Economy	$107	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/19/2026 5:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/20/2026 6:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 15m
	Greyhound US	27h 45m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	10:45 PM	San Antonio, TX	Bus Station		Economy	$111	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/19/2026 8:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/20/2026 10:45:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 27h 45m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 15m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	6:10 PM	San Antonio, TX	Bus Station		Economy	$107	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/21/2026 5:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/22/2026 6:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 15m
	Greyhound US	27h 45m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	10:45 PM	San Antonio, TX	Bus Station		Economy	$108	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/21/2026 8:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/22/2026 10:45:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 27h 45m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	29h 5m	8:00 PM	Knoxville, TN	Greyhound Bus Station	12:05 AM	San Antonio, TX	Bus Station		Economy	$109	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 9/24/2026 8:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/26/2026 12:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 29h 5m
	Greyhound US	25h 15m	5:55 PM	Knoxville, TN	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station		Economy	$112	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 9/24/2026 5:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/25/2026 6:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 25h 15m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 15m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	6:10 PM	San Antonio, TX	Bus Station		Economy	$114	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/25/2026 5:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/26/2026 6:10:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 25h 15m
	Greyhound US	27h 45m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	10:45 PM	San Antonio, TX	Bus Station		Economy	$115	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/25/2026 8:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/26/2026 10:45:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 27h 45m

Best Price Offer: The price for the cheapest bus from Knoxville, TN to San Antonio, TX is $99 on 9/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Knoxville, TN and San Antonio, TX

See here how frequent the connections between Knoxville, TN and San Antonio, TX are, during different times and days of the week.

Monday is the busiest day, with more than 4 daily buses from Knoxville, TN to San Antonio, TX. Thursday has instead the fewest connections, with only 2 daily coaches between Knoxville, TN and San Antonio, TX.

The busiest time of the day is the Afternoon, with 6 buses from Knoxville, TN to San Antonio, TX, while Afternoon sees the fewest connections between Knoxville, TN and San Antonio, TX, with 6 offers.

Facts about the bus from Knoxville, TN to San Antonio, TX

Compare all providers like Greyhound US that travel 3 times every day by bus from Knoxville, TN to San Antonio, TX in one click! Book your bus ticket from Knoxville, TN to San Antonio, TX starting from $99!

Cheapest Bus	$99
Fastest Bus	24h 15m
Earliest Bus	5:55 PM
Latest Bus	8:00 PM
Daily Bus Routes	3 Ø
Distance	958.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Knoxville, TN to San Antonio, TX

Every day, 3 buses from 1 bus companies leave Knoxville, TN for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/13

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

$107

Sunday 09/20

Monday 09/21

$111

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

$109

Friday 09/25

$117

Saturday 09/26

Sunday 09/27

Monday 09/28

Tuesday 09/29

$102

Wednesday 09/30

Thursday 10/01

Friday 10/02

$111

Saturday 10/03

Sunday 10/04

Monday 10/05

$113

Tuesday 10/06

$117

Wednesday 10/07

Thursday 10/08

$154

Friday 10/09

$155

Saturday 10/10

The cheapest time to travel from Knoxville, TN to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Knoxville, TN to San Antonio, TX, for the next 30 days.

With a price starting from $107, Monday is the cheapest day for a bus from Knoxville, TN to San Antonio, TX. Friday instead is the most expensive day with prices starting from $111.

Afternoon is the cheapest day time for bus tickets from Knoxville, TN to San Antonio, TX, with $107. Evening is the most expensive time of the day with prices starting from $108.

How to save money travelling from Knoxville, TN to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to San Antonio, TX are also emptier.

Beloved bus companies from Knoxville, TN to San Antonio, TX

These are the most booked bus companies between Knoxville, TN to San Antonio, TX from our users.

Greyhound US from Knoxville, TN to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route Knoxville, TN to San Antonio, TX:

Cheapest Price	$107
Fastest Bus	24h 15m
Earliest Bus	5:55 PM
Last Bus	8:00 PM
Daily Connections	3 Ø
Found on	8/26/2026

All bus stations and stops in Knoxville, TN and San Antonio, TX

In the map below, you can see where to find all bus stations in Knoxville, TN and San Antonio, TX.

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Transit Center

E Church Ave 301

Greyhound Bus Station

E Magnolia Ave 100

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Service and Comfort on the bus from Knoxville, TN to San Antonio, TX

Want to know which seat classes are available on the buses from Knoxville, TN to San Antonio, TX? Or which bus companies serve the route Knoxville, TN to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Knoxville, TN to San Antonio, TX bus

How much does a Knoxville, TN San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $99 and takes 24h 15m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to San Antonio, TX?

This route is offered by 1 companies with a range of ticket prices between $99 and $118. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Knoxville, TN to San Antonio, TX each day?

Every day, the Knoxville, TN to San Antonio, TX bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to San Antonio, TX take?

The fastest bus from Knoxville, TN to San Antonio, TX is offered by Greyhound US and takes 24h 15m. Bus tickets for this connection cost $107. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Knoxville, TN starts at 5:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to San Antonio, TX?

The latest bus trip departing from Knoxville, TN for San Antonio, TX starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN San Antonio, TX route?

When traveling by bus from Knoxville, TN to San Antonio, TX, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and San Antonio, TX?

You can check all the direct connections between Knoxville, TN and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Knoxville, TN and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to San Antonio, TX?

Prices and availability for 3 trips between Knoxville, TN and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to San Antonio, TX

Here’s an overview of the most popular bus routes to Knoxville, TN and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!